线粒体tRNA ser(UCN))基因突变致线粒体脑肌病1例并文献复习 维普资讯 http://www.cqvip.com
Identification of a modified nucleoside in Escherichia coli tRNA1Ser as 2'-O-methylcytidine. Biochim Biophys Acta. 1975 Sep 1; 402 (3):285–287.Yamada, Y., and Ishikura, H. 1975. Identification of a modified nucleoside in Escherichia coli tRNATer as 2’0-methylcytidine. Biochim. Biophys. ...
The 1.2 Å crystal structure of an E. coli tRNA Ser acceptor stem microhelix reveals two magnesium binding sites. Biochem Biophys Res Commun. 2009; 386 :368–373. doi: 10.1016/j.bbrc.2009.06.048. [ Cross Ref ]The 1.2A crystal structure of an E. co...
Sequence analysis of the complete mitochondrial genomes in these pedigrees showed the presence of the deafness-associated 12S rRNA C1494T and CO1/tRNASer(UCN) G7444A mutations. Their distinct sets of mtDNA polymorphism belonged to Eastern Asian haplogroup C4a1, while other previously identified six...
Here, we showed that NAT10 was lactylated by 伪-tubulin acetyltransferase 1 (ATAT1), as a writer at the critical domain, to exert RNA acetyltransferase function and thus increase the ac4C level of tRNASer-CGA-1-1. Mutagenesis at the ac4C site in tRNASer-CGA-1-1 inhibited its ac4C ...
Using a dual-luciferase reporter assay with firefly luciferase under the control of the HIV-1 long terminal repeat (LTR) promoter, we show that expression of the tRNA-TAR decoy chimera inhibits HIV-1 transcription in human HCT116 cells. We also show that mutations in the tRNA(Ser) acceptor ...
tRNA functionWe solved the X-ray structures of two Escherichia coli tRNA Ser acceptor stem microhelices. As both tRNAs are aminoacylated by the same seryl-tRNA-synthetase, we performed a comparative structure analysis of both duplexes to investigate the helical conformation, the hydration patterns ...
We found that most Saccharomycopsis species have genes for both tRNA-Leu(CAG) and tRNA-Ser(CAG). However, tRNA-Leu(CAG) has been lost in Saccharomycopsis synnaedendra and Saccharomycopsis microspora , and its predicted cloverleaf structure is aberrant in all the other Saccharomycopsis species. We...
Mutational analysis of the mitochondrial 12S rRNA and tRNASer(UCN) genes in Tunisian patients with nonsyndromic hearing loss. Biochem Biophys Res Commun. 2006; 340 :1251–1258.Mkaouar-Rebai, E., Tlili, A., Masmoudi, S., Louhichi, N., Charfeddine, I., Ben Amor, M., Lahmar, I., ...
携带线粒体CO1/tRNASer(UCN)7444G〉A突变和12SrRNA1555A〉G突变的非综合征性耳聋家系的线粒体功能研究 时雯雯2]陈亚茹2]任晓燕2]薛凌2]郑斌娇2]中国细胞生物学学报