网络电压门控钠离子通道;电压门控钠通道 网络释义 1. 电压门控钠离子通道 电压门控钠离子通道(voltage-gated sodium channels)是可兴奋细胞产生电兴奋的基础结构,其α亚单位为基本功能单位,可… www.ebiotrade.com|基于 1 个网页 2. 电压门控钠通道 ...
Furthermore,the external calcium was found to influx mainly through N-type calcium channels andvoltage-gated sodium channels. 我们进一步用膜通道阻断剂验证,发现胞外钙的流入主要是通过N型钙通道和电压门控钠通道流入胞内的。 更多例句>> 5) voltage-gated sodium currents ...
2) voltage-gated sodium channels 电压-门控Na+通道 1. Thevoltage-gated sodium channelshave a close relationship with epilepsy,and many epileptic syndromes are proved to be caused by mutations ofvoltage-gated sodium channels. 电压-门控Na+通道和癫痫的关系十分密切,许多癫痫综合征的发生已被证明是由Na...
Voltage-gated sodium channels (VGSCs) are transmembrane proteins that increase the permeability of sodium ions across membranes. The permeability of these channels depends on the voltage drop across the membrane. In a typical neuronal action potential, VGSCs remain closed until the membrane potential ...
Voltage-gated sodium channels (VGSC) are multi-molecular protein complexes expressed in both excitable and non-excitable cells. They are primarily formed by a pore-forming multi-spanning integral membrane glycoprotein (α-subunit) that can be associated with one or more regulatory β-subunits. The ...
Voltage-gated sodium channels subserve regenerative excitation throughout the nervous system, as well as in skeletal and cardiac muscle. This excitation results from a voltage-dependent mechanism that increases regeneratively and selectively the sodium conductance of the channel e-fold for a 4–7 mV...
Voltage-gated sodium (NaV) channels are a family of transmembrane ion channel proteins. They function by forming a gated, water-filled pore to help establish and control cell membrane potential via control of the flow of ions between the intracellular and the extracellular environments. Blockade of...
Voltage-gated sodium channels produce fast depolarization, which is responsible for the rising phase of the action potential in neurons, muscles and heart. These channels are very large membrane proteins and are encoded by ten genes in mammals. Sodium channels are a crucial component of excitable ...
Armed with these tools, researchers have made increasingly dramatic discoveries about sodium channels, culminating most recently in crystal structures of voltage-gated sodium channels from bacteria. These structures, along with those from other channels, give unprecedented insight into the structural basis ...
Painful stimuli are detected by specialized neurons, nociceptors, and are translated into action potentials, that are conducted along afferent pathways into the central nervous system, where they are conceived as pain. Voltage-gated sodium channels (Na V