Chapter 24. Ligand Gated and Voltage-Gated Ion Channels - ScienceDirectAccording to the nature of the primary regulating signal, most ion channels are classified as either ligand-gated or voltage-gated channels; however, these distinctions are not unique. The cell maintains an asymmetric ion ...
Carus H. Y. Lau1, Glenn F. King1 & Mehdi Mobli2 Voltage-sensor domains (VSDs) are modular transmembrane domains of voltage-gated ion channels that respond to changes in membrane potential by undergoing conformational changes that are coupled to gating of the ion-conducting ...
MICROSCOPY RESEARCH AND TECHNIQUE 50:403– 410 (2000) Neuromodulation of Ligand- and Voltage-Gated Channels in the Amphibian Retina ABRAM AKOPIAN* Department of Ophthalmology, New York University School of Medicine, New York, New York 10016 KEY WORDS patch clamp; whole-cell currents; ...
Voltage sensor domains comprise four transmembrane segments (S1 to S4) and are responsible for sensing changes in membrane potential and controlling gating of the pore domain (S5 and S6) in voltage-gated ion channels. Sasaki et al. (see the Perspective by Miller) have identified a protein consi...
Voltage-gated ion channels are membrane proteins that open and close an ion-selective pore in response to changes in transmembrane voltage. The charged S4 transmembrane helix transduces changes in transmembrane voltage into a change in protein internal energy by interacting with the rest of the ...
Probing Ion Channel Structure and Function Using Light-Sensitive Amino Acids Here, we review the diverse applications of light-sensitive UAAs in two superfamilies of ion channels (voltage- and ligand-gated ion channels; VGICs and... V Klippenstein,L Mony,P Paoletti - 《Trends in Biochemical Sc...
This book describes human hereditary ion channel diseases of voltage- and ligand-gated ion channels covering the diverse fields of medicine myology, neurology, ...K. JurkatRottF. LehmannHorn
Voltage-gated calcium channels in ligand- and voltage-gated ion channels (ed North, RA). Boca Raton (FL): CRC Press; 1995. p113–141. 5 Catterall WA. Structure and regulation of voltage-gated Ca2+ channels. Annu Rev Cell Dev Biol 2000; 16: 521–55. 6 Catterall WA, Perez-Reyes E,...
Modulation of cell viability, oxidative stress, calcium homeostasis, and voltage- and ligand-gated ion channels as common mechanisms of action of (mixtures of) non-dioxin-like polychlorinated biphenyis and polybrominated diphenylethers 来自 国家科技图书文献中心 喜欢 0 阅读量: 18 作者:...
Photoactivatable drugs targeting ligand-gated ion channels open up new opportunities for light-guided therapeutic interventions. Photoactivable toxins targeting ion channels have the potential to control excitable cell activities with low invasiveness an