Ligand-gated ion channels (LGICs) are fast-responding channels in which the receptor, which binds the activating molecule (the ligand), and the ion channel are part of the same nanomolecular protein complex. This chapter will describe the properties and functions of the nicotinic acetylcholine LG...
ligand-gated ion channels基本解释 配体门控离子通道;配基门控离子通道;配体依赖性离子通道 分词解释 ion〈物〉离子 channels频道( channel的名词复数 ) 猜你喜欢 marketing channels营销渠道 channels of distribution销售渠道 commercial channels商业频道 diplomatic channels外交途径 financing channels融资渠道 gated ...
The study of ligand-gated ion channels has been dominated by the molecular identification of multiple receptor isoforms and their extensive biophysical characterisation. More recently, the cellular mechanisms which regulate receptor localisation and function have become a focus of attention. Here, we conce...
•Channelstructure –Heteropentamer–4-transmembranepasssubunits •Neurotransmitterdiversity•Postsynapticpotentials –Excitatory–Inhibitory •Modulation Structure •Pentameric•Chargedpore –Cation/anionselective–4-passmonomer •Cytoplasmicbasket Receptoractivation •2-5ligandsperchannel •Ionselectivity...
ligand-gated ion channel 相关知识点: 试题来源: 解析 配体门控通道是仅在细胞外的配体(如乙酰胆碱等化学信号)与细胞表面的受体结合时发生反应引起通道蛋白构象发生改变.使闸门开放的离子通道。配体门控通道,是仅在细胞外的配体(如乙酰胆碱等化学信号)与细胞表面的受体结合时发生反应,引起通道蛋白构象发生改变.使...
Structure •Pentameric•Chargedpore –Cation/anionselective–4-passmonomer •Cytoplasmicbasket Receptoractivation •2-5ligandsperchannel •Ionselectivity•Inactivation Neurotransmitters TransmitterInotropicreceptor Structure AcetylcholineExcitatory(nicotinic)Na/Kchannel GlutamateSerotonin ExcitatoryNa/Ca/KNMDA/...
5. 许多神经递质的受体蛋白是配体门控离子通道(ligand gated ion channel) 6. 在某些情况下神经效应物 …www.docin.com|基于2个网页 2. 配体闸门离子通道 ...ltage gated ion channel),配体闸门离子通道(Ligand gated ion channel)和伸展激活离子通道(Stretch activated ion channel) …www.ssbiophysics.com.cn...
There is progress in the study of ligand-gated ion channel function and structure but many new issues are raised concerning the function of this important class of membrane proteins. 展开 关键词: General anaesthesia, ligand-gated ion channels, GABA, glutamine, acetylcholine, glycine, serotonin, ...
ion n. 【物,化】离子 channel n.[C] 1. 河床 2.(液体的)通道 3. 航道 4. 海峡 5.(新闻、信息等传递的)途径,线路 6. 频道;某电视台 v.[T] 1. 在(某物)上形成槽或沟 2. 经水 bio ligand 【化】 生物配体 resin ligand 树脂配合体 laser gated 激光选通 hydronium(ion) 水合氢 最...
Anion/cation selectivity is a critical property of ion channels and underpins their physiological function. Recently, there have been numerous mutagenesis studies, which have mapped sites within the ion channel-forming segments of ligand-gated ion channels that are determinants of the ion selectivity. ...