Functional expression of voltage-gated calcium channels in human melanoma. Pigment Cell Melanoma Res 25, 200-212.A.Das,C.Pushparaj,N.Bahí,A.Sorolla,J.Herreros,R.Pamplona,R.Vilella,X.Matias‐Guiu,R. M.Martí,C.Cantí.Functional expression of voltage‐gated calcium channels in human melanoma[...
Voltage-gated calcium channels (CaV) are a family of complex proteins that conduct Ca2+into the cell cytoplasm through a large pore-forming α1subunit of 190–250 kDa. They are divided into three major families CaV1.x, CaV2.x, and CaV3.x based on sequence homology of the α1subunit. ...
The majority of the structure/function information about voltage-gated calcium channels has been deduced from site-directed mutagenesis and generation of chimeric calcium channel subunits. Based on the crystal structures of potassium channels, several homology models of Cavα1 subunits have been constructe...
"Voltage Gated Calcium Channels" is the first comprehensive book in the calcium channel field, encompassing over thirty years of progress towards our understanding of calcium channel structure, function, regulation, physiology, pharmacology, and genetics. This book balances contributions from many of the...
Voltage-gated calcium channels (CaVs) are large, transmembrane multiprotein complexes that couple membrane depolarization to cellular calcium entry. These ... F Findeisen,DL Mi - 《Channels》 被引量: 163发表: 2010年 Structure and Function of Voltage-Dependent Ion Channel Regulatory β Subunits Volta...
The role of L-type voltage-gated calcium channels Cav1.2 and Cav1.3 in normal and pathological brain function The use of specific activators and inhibitors that penetrate the central nervous system has suggested an essential functional role of L-type calcium channe... SM Berger,D Bartsch - 《Ce...
Voltage-gated calcium channels function in excitation–contraction (EC) coupling, excitation-secretion coupling, neurotransmitter release, regulation of gene expression and neuronal migration. Two classes of voltage-gated calcium channels have been described. The first class are high-voltage-gated channels,...
Voltage-gated ca2+-channel alpha 1-subunit de novo missense mutations: gain or loss of function - implications for potential therapies. Front. Synaptic Neurosci. 13, 634760 (2021). McDavid, S. & Currie, K. P. G-proteins modulate cumulative inactivation of N-type (Cav2.2) calcium channels....
Voltage-gated calcium channels (VGCCs) enable calcium influx during cell membrane depolarization and are essential for a range of physiological functions such as neurotransmission, muscular contraction, membrane excitability, synaptic plasticity, and gene expression. Read More......
Voltage-gated calcium channels (VGCCs) are a large and functionally diverse group of membrane ion channels ubiquitously expressed throughout the central and peripheral nervous systems. VGCCs contribute to various physiological processes and transduce electrical activity into other cellular functions. This ...