A medical material for in vivo implantation use, characterized in that a polyethylene terephthalate ultrafine fiber is provided in at least a part of the medical material, wherein the polyethylene terephthalate ultrafine fiber is produced by spinning a polyethylene terephthalate chip, which is produced...
Long-term studies correlating biochemical changes to observable clinical improvements may clarify this. Finally, our findings suggest that cross-linked hyaluronic acid may have application as a stimulator of collagen in conditions of collagen deficiency, including atrophic skin disorders (eg, human ...
Need a short-term in-vivo catheter material that meets your formulation specifications, but don’t have the time or ability to manufacture it in-house? NEU™ Custom Capabilities can help. More From the Idea Center Idea Center What's the Difference™? TPEs vs. Silicones ...
A medical material for in vivo implantation use, characterized in that a polyethylene terephthalate ultrafine fiber is provided in at least a part of the medical material, wherein the polyethylene terephthalate ultrafine fiber is produced by spinning a polyethylene terephthalate chip, which is produced...
The in vivo performance of nanomedicines which determines the therapeutic efficacy and safety is believed to be heavily influenced by the physio-pathological characters of the body. Activation of multiple immune factors, e.g., complement system, phagocytic cells, lymphocytes, and among many others, ...
J.W.Kille, inA Comprehensive Guide to Toxicology in Nonclinical Drug Development (Second Edition), 2017 Developing the Nonclinical Toxicology Program The nonclinical (a term often used interchangeably with “preclinical”) toxicity testing of a new drug, whether it be a small-molecule or biotechnolog...
A number of earlier C7 replacement strategies have been evaluated for RDEB8. The first approach, bone marrow transplantation, promoted C7 expression and wound healing; however, long-term results remain unclear and the procedure is associated with a mortality rate approaching 30%9. Another earlier ap...
To determine the in vivo loads on the hip joint, an instrumented implant with a titanium alloy stem (TiAl6V4) and a 32 mm ceramic head (Al2O3) was used. The prosthesis is based on a clinically proven cementless standard implant (CTW, Merete Medical, Berlin, Germany).The implant was al...
3.2. CTC Short-Term Culture from Metastatic Breast Cancer Patients 3.2.1. CTC Culture Characterization CTCs isolated using a negative enrichment approach (RosettesepTM), were plated under non-adherent conditions, in MammoCult media supplemented with growth factors plus NEs and under hypoxic conditions ...
Safety concerns regarding stem cell-derived neoplasia were addressed using whole-body In Vivo Imaging System (IVIS) imaging. Luciferase signal was detectable only in the heart, but not in other organs, suggesting a non-invasive nature of the progenitors and long-term viability throughout the 12-...