The ECM turnover is upregulated in fibrosis, meaning that the cell population will fluctuate, which may also be very important regarding changes in cell behavior (Chang et al., 2002; Chipev and Simon, 2002). Another important factor when working with a disease model is the induction of the...
(84) provided some useful data on the Se and Sp of the SICTT in the GB bTB eradication programme namely that in GB, Sp at animal level is 99.983 (standard inter- pretation) and 99.871 (ultra-severe interpretation), meaning that one false positive can be expected at s...
Cohort sizes for preclinical studies can also be further reduced by using the same animal for multiple PK analyses. Through the use of NIR-II, researchers could use in vivo imaging earlier in the probe validation process, meaning NIR-II would have a much more fundamental role in compound scree...
Statements in this press release about future expectations, plans and prospects, as well as any other statements regarding matters that are not historical facts, may constitute "forward-looking statements" within the meaning of The Private Securities Litigation Reform Act of 1995. These statements incl...
It is known that β cell proliferation expands the β cell mass during development and under certain hyperglycemic conditions in the adult, a process that may be used for β cell regeneration in diabetes. Here, through a new high-throughput screen using
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which the invention belongs. Although any methods and materials similar to or equivalent to those described herein can be used in the practi...
Here, we used a noninvasive multimodality imaging approach to monitor differentiation of transplanted bone marrow mesenchymal stem cells (BMSCs) and recovery of cardiac function in an in vivo model of myocardial infarction (MI). We established a rat MI m
At the beginning of the test, when the load was applied, the bone specimen deformed elastically, meaning it returned to its original shape upon removal of the load. In this phase, the force–displacement curve shows a linear relationship, indicating proportional loading and deformation. From the...
(meaning a total of only 1 to 6 double positive cells in the cerebellum of each larvae, being only of 0.9% of the totalFabp7enhancer-controlled fluorescent protein-expressing cell population as well), which may represent maintainedFabp7regulatory element-mediated reporter expression in very early ...
Unless otherwise defined herein or below in the remainder of the specification, all technical and scientific terms used herein have the same meaning as commonly understood by those of ordinary skill in the art to which the invention belongs. BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 schematically ...