IV to Oral Vitamin D Switch BeneficialThe article reports on a study by Canadian researchers which found that switching from intravenous (IV) to oral activated vitamin D drug may offer similar control of secondary...
Vitamin K is essential for several physiological processes, such as blood coagulation, in which it serves as a cofactor for the conversion of peptide-bound glutamate to γ-carboxyglutamate in vitamin K-dependent proteins. This process is driven by the vitamin K cycle facilitated by γ-carboxyglutam...
Interestingly, although VKORC1L1 carries out the same two enzymatic steps of the vitamin K cycle as does VKORC1, it appears to be far less sensitive to oral anticoagulant drugs, suggesting that its biological activity may not be substantially reduced when oral anticoagulants ...
IV administration. Oral high-dose preparation of vitamin A (no longer commercially available in the US): Malabsorption syndromes. Hypervitaminosis A. Known sensitivity to vitamin A or any ingredient in the formulations. Dosages exceeding RDA contraindicated in women who are or may become pregnant....
Vitamin D is classified as an immunomodulatory hormone that is synthesized because of skin exposure to sunlight. It is known to come into play during the regulation of hormone secretion, immune functions, cell proliferation, and differentiation. Its defi
Check access to the full text by signing in through your organization. Access through your organization Section snippets History The therapeutic efficacy of animal liver (via local application or oral ingestion) against blindness and keratomalacia has been known since antiquity. In 1913, McCollum ...
The conversion is catalyzed by a specific microsomal enzyme, vitamin D-25-hydroxylase. Recent findings indicate that homogenates of chick small intestine and kidney are also able to hydroxylate vitamin D. It is not known whether such extrahepatic 25-hydroxylation takes place in man. Early ...
Effect of Different Dosages of Oral Vitamin D Supplementation on Vitamin D Status in Healthy, Breastfed Infants.Effect of Different Dosages of Oral Vitamin D Supplementation on Vitamin D Status in Healthy, Breastfed Infants.The article presents a research which aims to analyze the effectiveness of...
thermosensitiveisomerizationtovitamin D3(Bikle, 2014). Most of thevitamin Dneeded for cellular functions is obtained by natural sunlight conversion or by oral vitamin D supplementation (Wolf, 2019;Young et al., 2019).Vitamin D receptor(VDR) is expressed ubiquitously. Roughly 5% of thehuman ...
[1]. While oral intake is an important source of vitamin D, the major physiological source is UVB irradiation at a wavelength of 290–315 nm [2]. The ability of the skin to synthesise vitamin D is compromised at northerly latitudes, particularly amongst those who are older or who have ...