In 1975, it was demonstrated that crude rat liver microsomal preparation contained an enzymatic activity (the vitamin K-dependent carboxylase) that promoted a vitamin K-dependent incorporation of H14CO3− into Gla residues of endogenous precursors of vitamin K-dependent proteins present in these prep...
dogs. Activated charcoal comes in a liquid and it’s thought to help bind and clear the toxins. Again, this is ideally given within a few hours of ingestion, but there was really very little downside to giving it at 12 hours post-exposure, so we tried it. Most dogs will not eat ...
For those of us farther from the equator, we only get a little bit of UVB, usually in the middle of the day and during summer months. By comparison, people living in countries closer to the equator are bathed in UVB year-round for most of the day. But new research shows that the an...
In 1942, Link himself set up field trials to test the suitability of dicoumarol as a rat poison. Tests by O’Connor (1948) using a concentration of 0.44 mg/g were reported as highly successful. However, tests carried out by the U.S. Public Health Service (Hayes and Gaines...
6.1. Osteocalcin Like all VKDP proteins, OC requires vitamin K for the γ-glutamylcarboxylation of three glutamate-residues, which in turn confers functional protein activity. In tissues and the circulation OC is present in both the carboxylated (cOC) and uncarboxylated (ucOC) conformations. OC ...