Harmeyer J,Schlumbohmb C (2004).Effects of pharmacological doses of vitamin D3 on mineral balance and profiles of plasma vitamin D3 metabolites in horses. J. Steroid Biochem. Mol. Biol. 89-90: 595-600. http://dx.doi.org/10.1016/j. jsbmb.2004.03.034...
A double-blind, randomized, placebo-controlled trial (N=50) assessing use of ergocalciferol in patients with uremic pruritus was 1 of 10 new studies added to the 2016 updated Cochrane systematic review of pharmacological interventions for pruritus in adult palliative care. After either oral ergocalc...
We also show that blocking 1,25D3-triggered autophagy with pharmacological inhibitors or RNA interference decreases the inhibition of HIV-1 replication. Therefore, this study demonstrates, to our knowledge for the first time, that 1,25D3 inhibits HIV-1 replication through the induction of autophagy...
Vasques F, Camporota L and Barrett NA: Nonantibiotic pharmacological treatment of severe chronic obstructive pulmonary disease exacerbations. Semin Respir Crit Care Med. 41:842–850. 2020.PubMed/NCBIView Article:Google Scholar 8 Kim V and Criner GJ: Chronic bronchitis and chronic obstructive pulmona...
fluorescent nutrient analogues, mitochondrial dyes, measurement of oxygen consumption and in-depth, mass-spectrometry based metabolic tracing of isotope-labelled nutrients. Specific metabolic pathways will be linked to defined immunological phenotypes and inflammatory functions using established pharmacological ...
In vitro studies have shown that a pharmacological dose of 1,25(OH)2D3 upregulated the mRNA and protein expression of the insulin receptor, which translated into a greater insulin-induced glucose transport.122 Among other mechanisms, vitamin D may modulate insulin sensitivity through its effect on...
In this study, we determined 251 differentially expressed proteins regulated by VD3 through proteomics analysis to further study the pharmacological effects of VD3 in the treatment of IPF. GO analysis showed that VD3 has multiple effects, including acute inflammation, response to oxidative stress, antio...
A wide variety of factors, including PTH [71], pharmacological activators of the protein kinase A pathway [72], transforming growth factor β (TGFβ) [73], estrogens [74], thyroid hormone [75], glucocorticoids [76], and retinoic acid [77] can alter VDR mRNA levels in a tissue-specific...
The present inventor have extensively worked for vitamin D3derivatives having excellent pharmacological effects, particularly excellent bone forming activity, and low toxicity, and have now found that by introducing two fluorine atoms into the carbon atom at the 24-position of vitamin D3and a methyl...
Holmberg et al., “Absorption of a Pharmacological Dose of Vitamin D3 From Two Different Lipid Vehicles in Man: Comparison of Peanut Oil and a Medium Chain Triglyceride”, Biopharmaceutics & Drug Disposition, 1990, pp. 807-815, vol. 11. ...