colon cancer cells can develop resistance to 1α,25(OH) 2 D 3 action due to aberrant expression of the enzymes responsible for its synthesis and catabolism or to the down-regulation of vitamin D receptor, a ligand-regulated transcription factor that mediates most 1α,25(OH) 2 D 3 actions...
colon cancer cells can develop resistance to 1α,25(OH) 2 D 3 action due to aberrant expression of the enzymes responsible for its synthesis and catabolism or to the down-regulation of vitamin D receptor, a ligand-regulated transcription factor that mediates most 1α,25(OH) 2 D 3 actions...
I. M., Stampfer, M. J., ... & Ma, J. (2011). Circulating levels of vitamin D and colon and rectal cancer: the Physicians9 Health Study and a meta-analysis of prospective studies. Cancer prevention research, canprevres-0289.
Objective: To investigate whether prognosis of breast-, colon- and prostate cancer may be related to vitamin D3, induced from solar ultra-violet (UV) radiation, through studies on geographical and seasonal variations in UV radiation. Methods: This study includes 115,096 cases of breast-, colon...
Role of Folate in Colon Cancer Development and Progression. Folate, a water-soluble B vitamin and important cofactor in 1-carbon transfer, is an important nutritional factor that may modulate the development of colo... Young-In,Kim - 《Journal of Nutrition》 被引量: 444发表: 2003年 Cancer ...
Vitamin D(VD)对人体健康的影响颇为广泛。骨化三醇作为生物活性最高的一种VD形式,在除了保持人体钙平衡以外,其对抗恶性细胞增生和促恶性细胞分化的作用被研究者发现之后,VD作为抗癌防癌治疗的药物的可能性也倍受关注[1]。 《极养智库》编辑团队原创版权
Do Sunlight and Vitamin D Reduce the Likelihood of Colon Cancer? International Journal of Epidemiology 1980;9:227-31. [9] Garland F, Garland C, Gorham E, Young J. Geographic variation in breast cancer mortality in the United States: a hypothesis involving exposure to solar radiation. ...
Colon cancer Caco-2 cells were obtained from BeNa Culture Collection (Kunshan, China). Vitamin D3 (purity of 98%) was purchased from Yuanye Biotechnology Co., Ltd (Shanghai, China). Flavourzyme (1.1 × 105 U/g) was purchased from Novozymes Biotechnology Co., Ltd (Tianjin, China). Pyrene...
Specifically, sunlight protects against ovarian, breast, prostate, and colon cancer [40]. On the other hand, vitamin D3 deficiency enhances the risk of several malignancies, including gonadal tumors [41]. Consistent with this effect, multiple ovarian and testicular cancer cell lines respond to ...
The majority of cancer cell types, including HL60 leukemia, Coco and HT29 human colon cancer cells and a variety of prostate cancer cells including LnCap cells are all responsive to vitamin D analogs [34]. More recently it was noted that the incubation of prostate cancer cells as well as ...