Vitamin D3 in cancer prevention and therapy: the nu- tritional issue. Horm Mol Biol Clin Investig 2015;23:71-8.A. Chirumbolo, "Vitamin D3 in cancer prevention and therapy: the nutritional issue," Hormone Molecular Biology and Clinical Investigation, vol. 23, no. 5, pp. 71-78, 2015....
A low serum level of vitamin D has been associated with an increased incidence of gastrointestinal tract cancers. However, the effects of vitamin D3 have not been investigated in gastric cancer and cholangiocarcinoma. In the present study, we found that vitamin D3 treatment significantly suppressed...
Cancer cells, including breast, have high glycolysis rates to meet their energy demands for survival and growth. Vitamin D-3 (VD3) is important for many important physiological processes such as bone mineralization, but its anticancer role is yet to be proven. We find that VD3 treatment ...
Objective To study the effect of vitamin D3 on breast cancer xenografted on a nude mouse model. MethodBalb/c nude mouse was injected subcutaneously with 10 6 human breast cancer cell line MCF-7.Two thousand units Vitamin D3 was administered in mice i·m every the other day. Tamoxifen (5...
Calcitriol (1,25-dihydroxyvitamin D3), the hormonally active form of vitamin D, exerts growth inhibitory and prodifferentiating effects on many malignant c... Aruna,V.,Krishnan,... - 《Rheum Dis Clin North Am》 被引量: 431发表: 2012年 Treatment of pancreatic cancer with active vitamin d ...
Consequently, Vitamin D3 and Vitamin D3 analogues, utilized at concentrations which produce limited hypercalcemia, are likely to prove effective as adjuncts to conventional chemotherapy and radiotherapy. 展开 关键词: vitamin d radiotherapy minimal toxicity cancer therapeutic current clinical protocol ...
Vitamin D3 intake and sunlight exposure have a protective effect against colorectal cancer (CRC) and other neoplasias. In line with epidemiological data, the most active metabolite of vitamin D3,1α, 25-dihydroxyvitamin D3, [1α,25(OH)2D3] has...
and What does the study add?Cryoblation is a highly effective treatment for prostate cancer yet concerns of recurrance remain due to cell survival in the periphery of the frozen volume of tissue where lethal temperatures may not be achieved. To improve efficiency research has focused on the ...
intriguing novel anti-neoplastic agents is 1,25-dihydroxyvitamin D3 [(1,25(OH)2D3), calcitriol], the hormone first identified as an effective treatment for rickets, which has recently garnered wide-spread support as a possible anti-neoplastic agent in a number of different cancer subtypes ...
Importantly, Vit D3 significantly sensitized prostate cancer cell to radiation doses from 0.5 to 4.0 Gy, demonstrating the potential efficacy of Vit D3 for enhancing radiation treatment with clinical relevant doses. Treatment of prostate cancer cells with Vit D3 suppresses the expression of RelB ...