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Vitamin D’s major function is to support bone health by enhancing calcium and phosphorus absorption and maintaining healthy blood levels of these minerals.? In addition, Vitamin D can help to maintain a healthy immune system.? [Vitamin D may regulate and support normal functions of immune cells...
Sunshine is the major source of vitamin D for most humans on the planet. When the ultraviolet (UV) light from the sun penetrates human skin, it triggers a chemical reaction that generates vitamin D. If a person with fair skin goes out in the sun for about 20 minutes wearing a bathing ...
There are two major isoforms of vitamin D, vitamin D2(ergocalciferol), and vitamin D3(cholecalciferol)21,22. Vitamin D2is synthesized from ergosterol by UVB radiation in plants, yeasts, and fungi and can be ingested in a diet containing plant source foods, such as mushrooms. Vitamin D3is ...
Vitamin D can help in the following body functions: Immune system by fighting off infections Brain development Muscle function Anticancer effects Respiratory system (for healthy airways and lungs) Cardiovascular system (for a healthy heart and normal blood circulation) ...
Optimal vitamin D status can be defined as the daily intake or production of the vitamin (and/or the serum level of 25(OH)D) that is sufficient so that its availability does not limit any of the metabolic functions dependent on the vitamin. ...
(OH)2D3], the hormonally active form of vitamin D, is the major controlling hormone of intestinal calcium absorption.4Calcium homeostasis is also regulated by parathyroid hormone and ionized calcium.1,5This review will focus on mechanisms involved in vitamin D regulation of calcium homeostasis, ...
10,11,21, 22, 23 Once entering the circulation, vitamin D (vitamin D2 and D3) is converted by several vitamin D-25-hydroxylases (ie, CYP2R1, CYP27A1, CYP2C11, CYP2J3, CYP3A4) in the liver into 25(OH)D, the major circulating metabolite of vitamin D. 25(OH)D is then ...
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Vitamin D plays an important role in modulating steroidogenesis by regulating the expression of several genes encoding steroidogenic enzymes and of most relevance to this study, CYP19A1 the gene coding for aromatase which is the major catabolic enzyme in testosterone elimination (see Fig. 1a) [25...