One of the main functions ofvitamin D is to help activate T cells, aka the "killer cells" in the body. T cells actually detect and destroy foreign pathogens -- like viruses. "That makes vitamin D especially crucial for maintaining a functioning immune system that's capable of fighting back...
Vitamin D exerts its effects by binding to and activating the vitamin D receptor (VDR). Upon binding vitamin D, the VDR functions as a transcription factor, regulating the activity of over 1,000 different genes.[14] This “genomic” action of vitamin D tends to be slower-acting, requiring...
Just like other vitamins and minerals, vitamin D plays a key role in many important body functions.【小题1】Not getting enough vitamin D can lead to weak bones, muscle weakness, and even cancer.Besides getting 10 to 15 minutes of sun exposure each day, consider including the following foods...
摘要: Provides information on the function of vitamin D. Information on the functions of the vitamin D hormone, 1,25-dihydroxyvitamin D by way of a nuclear receptor (vitamin D receptor, VDR); Binding of VDR to the direct repeat response elements called DR-3; What the binding requires....
Analysis of the main functions altered by vitamin D supplementation using the Ingenuity Pathway Analysis Tool.JeanFrancois, Chabas
The vitamin D endocrine system is critical for the proper development and maintenance of mineral ion homeostasis and skeletal integrity. Beyond these classical roles, recent evidence suggests that the bioactive metabolite of vitamin D, 1,25-dihydroxyvitamin D3, functions in diverse physiological processes...
though they are also designated by chemical names, such asniacinandfolic acid. Biochemists traditionally separate them into two groups, the water-soluble vitamins and the fat-soluble vitamins. The common and chemical names of vitamins of both groups, along with their main biological functions and...
Vitamin D3has a superior bioavailability than vitamin D2; nonetheless, they both go through the same metabolic pathway to produce the active hormonal forms [4,10]. Vitamin D is biologically inert and has to undergo hydroxylation twice before it can perform its physiological functions. Vitamin D ...
‘main effects’ (for example, receiving vitamin D versus not receiving vitamin D while adjusting for other treatments). Alternatively, in the case of interactions between treatments, each treatment arm was compared to the placebo arm. The models were adjusted for chronological age (continuous and ...
10,11 Furthermore, CYP27B1 is expressed in several other tissues, including parathyroid glands, breast, colon, keratinocytes, microglia, and immune cells, where 1,25(OH)2D is produced and exerts its autocrine, paracrine, and intracrine functions by binding with the intracellular vitamin D ...