Vitamin D deficiency is highly prevalent among children and adolescents worldwide. The high rates of vitamin D deficiency during childhood are of major public health relevance, given the growing evidence that vitamin D deficiency may play a key role in the pathophysiology of many chronic diseases be...
The concern about the assessment of vitamin D status is growing. Numerous publications warn about the high prevalence of vitamin D deficiency, as well as the potential role of vitamin D in non-bone health outcomes. The status of vitamin D is usually asse
In a separate group of regularly transfused children with SCA, we compared changes in 25-OHD blood concentrations following treatment with either high-dose intramuscular ergocalciferol ( n =15) or 4days of high-dose oral cholecalciferol ( n =64). Ninety-one percent of children with SCA had ...
Vitamin D deficiency can result from inadequate exposure to sunlight; malabsorption; accelerated catabolism from certain medications; and, in infants, the minimal amount of vitamin D found in breast milk. In children, vitamin D deficiency can result in r
Note that several members of the IOM committee publicly stated that over screening for vitamin D deficiency was a problem which typically resulted in unnecessary treatment. They were not in agreement with a cut-off level of 20 ng/ml for deficiency and recommended a lower level of 12.5 ng/ml....
In 1974 we reported the results of a controlled study of the prevalence and treatment of rickets in 60 epileptic adolescent children, compared with a matched group of non-epileptic children living in the same institution in Southeast England.5Biochemical evidence of vitamin D deficiency was more ...
Consequently, a vitamin D deficiency in obese children seems to be associated with a significant increase of risk of many metabolic disorders associated with obesity, such as insulin resistance, hyperinsulinemia, impaired tolerance of glucose, abnormal fasting plasma glucose, symptomatic diabetes mellitus,...
Homeostatic Model Assessment of Insulin Resistance; HOMA-IR; vitamin D deficiency; type 2 diabetes (T2D); body mass index; BMI; insulin resistance1. Introduction A secosteroid hormone, vitamin D has a variety of pathologic and physiologic functions in the human body. In addition to its function...
Vitamin D Deficiency Treatment In the U.S., the recommended dietary allowance (RDA) of vitamin D is as follows: For infants and babies: 400 international units (IU) a day For children and teens aged 1-18 years: 600 IU a day For adults aged 19-70 years: 600 IU a day ...
Being that the sun is the primary source of vitamin D, your exposure, or lack of it, will impact your risk for a deficiency. The Endocrine Society recommends screening and treatment for individuals at risk, including older adults with a history of falls or nontraumatic fractures; obese childr...