There are increasing numbers of children living with medical conditions in which either the condition or the treatment predisposes them to poor bone health and threatens their ability to attain peak bone mass. An understanding of calcium homeostasis and normal bone growth and development is essential ...
Vitamin D deficiency has emerged as a significant public health problem throughout the world. Even in the Indian context,it has been reported to be present in majority of children in spite of wide availability of sunlight. Recent guidelines have defined vitamin D status as severe deficiency, defi...
There are few data which document the epidemiology of serum 25(OH)D concentrations across the general population, but studies in selected groups often report a high prevalence of VDD. Two recent large studies in the United Kingdom (UK) demonstrated that around a third of children had a serum ...
Studies performed on Indian children to assess vitamin-D status have been on small sample sizes, limited to specific geographical locations and used non-standard methods to measure 25(OH)D3. This multicentre study assessed 25(OH)D3concentrations from dried blood spots (DBS) in 5–18-year-old ...
Note that several members of the IOM committee publicly stated that over screening for vitamin D deficiency was a problem which typically resulted in unnecessary treatment. They were not in agreement with a cut-off level of 20 ng/ml for deficiency and recommended a lower level of 12.5 ng/ml....
VitaminDaffectsinnateandadaptiveimmunityprocessesthatimpacttreatment,severity, andmorbidityofacuteasthmaepisodes.SeveralvitaminDformsmayhelpmodulate immunity,includingvitaminD2(D2),vitaminD3(D3),25-hydroxyvitaminD3 (25(OH)D3),and1,25-dihydroxyvitaminD3(1,25-(OH)2D3).Thisstudyassessedserum levelsofvitam...
All children or adults lacking sufficient exposure to sunlight need a vitamin D supplement; however, no agreement has been reached regarding dosage, and implementation is poor The WHO, supported by its member states, should implement a strategy to eradicate vitamin D (and calcium) deficiency-associa...
Osteoporosis in men: epidemiology, diagnosis, prevention, and treatment. Clin Ther. 2004;26(1):15-28.PubMedGoogle ScholarCrossref 14. Jackson RD, LaCroix AZ, Gass M, et al; Women’s Health Initiative Investigators. Calcium plus vitamin D supplementation and the risk of fractures. N Engl...
Vitamin D Supplementation in Children: Indian Perspectives Chapter © 2013 Indian Academy of Pediatrics Revised (2021) Guidelines on Prevention and Treatment of Vitamin D Deficiency and Rickets Article 29 December 2021 Abbreviations 1,25(OH)2D: 1,25-dihydroxyvitamin D 25(OH)D: 25-hydroxyvita...
It is figured out that a higher number of randomized controlled trials are essential to evaluate efficacy pertaining to clinical cases, treatment duration, type, and dose of supplementation and pathophysiology of diseases, immune system functioning, and the effect of vitamin D to be administered. ...