In vitro and in vivo studies have provided understanding of an underlying mechanism for the vitamin D effect. However, recently there has been increased intensity in vitamin D/cancer research after publication of a randomized trial that found that vitamin D 3 and calcium reduced the risk of all...
Vitamin D exerts anti-cancer effects in recent clinical trials and preclinical models. The actions of vitamin D are primarily mediated through its hormonal form, 1,25-dihydroxyvitamin D (1,25(OH)2D). Previous literature describingin vitrostudies has predominantly focused on the anti-tumourigenic ...
4. Epigenetic basis of vitamin D signaling 5. The vitamin D transcriptome and cancer 6. Impact of the immune system on the anti-cancer role of vitamin D 7. Vitamin D and CRC 8. Vitamin D and breast cancer 9. Vitamin D and prostate cancer 10. Vitamin D and hematological malignancies 11...
2023年7月20日，香港中文大学于君、胡嘉麒（William Ka Kei Wu）及Matthew Tak Vai Chan共同通讯在Cancer Cell 在线发表了题为“Carnobacterium maltaromaticum boosts intestinal vitamin D production to suppress colorectal cancer in female mice”的研究论文，该研究发现在两种小鼠CRC模型中，给予麦芽香肉杆菌能以雌...
Description Vitamin D aids in the absorption of calcium and has central roles in bone formation and maintenance, hypertension, cancer and immunity. Vitamin D may be obtained from many dietary sources, including eggs and fish, and is synthesized in the skin by the conversion of 7-dehydrocholestero...
R. The effect of vitamin D supplementation on skeletal, vascular, or cancer outcomes: a trial sequential meta-analysis. Lancet Diabetes Endocrinol. 2, 307–320 (2014). Article CAS PubMed Google Scholar Kanis, J. A. et al. European guidance for the diagnosis and management of osteoporosis...
2. Experimental basis for vitamin D and cancer For the past 20 years it has been consistently reported and well established that the active metabolite of vitamin D, 1,25(OH)2D3 exhibits potent cell differentiating property in leukemia cells as well as much cancer cells [13], [14]. The an...
Vitamin D deficiency has pleiotropic effects on the human body and is associated with related health and diseases such as bone and dental health, cardiovascular disease, hypertension, some types of cancer, types 1 and 2 diabetes, obesity, multiple sclerosis, cognitive decline, dementia, depression,...
cancer cells employ several mechanisms that reduce cellular calcitriol levels, as well as diminish its function to protect themselves from the antitumorigenic effects of vitamin D17,18. Thus, understanding how vitamin D metabolism and signaling are dysregulated in cancer will help develop efficient ...
Substances Added to Food (formerly EAFUS) VITAMIN D-3 EWG's Food Scores 2-5 FDA UNII 1C6V77QF41 NCI Dictionary of Cancer Terms cholecalciferol NCI Drug Dictionary cholecalciferol NIST Chemistry Reference Cholecalciferol(67-97-0) EPA Substance Registry System Cholecalciferol (67-97-0) ...