Vitamin D, traditionally known as an essential nutrient, is a precursor of a potent steroid hormone that regulates a broad spectrum of physiological processes. In addition to its classical roles in bone metabolism, epidemiological, preclinical, and cellular research during the last decades, it reveale...
Vitamin D status and its association with gradual decline in cognitive function To compare plasma vitamin D concentrations among patients with normal cognitive function (control group), mild cognitive impairment (MCI), and Alzheimer disease (AD). In total, 158 patients with AD, 228 patients with ...
Vitamin D and Immune Function Due to the presence of the VDR in most tissues, including the skin, skeletal muscle, adipose tissue, endocrine pancreas, immune cells, and blood vessels, vitamin D has been shown to have a multitude of nonskeletal biological activities. In particular, vitamin D ...
Vitamin D is essential for bone-building, cognitive function, joint health, immune function, blood sugar control, positive mood and more. It can help prevent many diseases. Some studies suggest that the lower your vitamin D level is, the higher your risk of death from any cause will be. Ho...
Vitamin D is necessary for bone-building, immune function, blood sugar control, positive mood and more.(1)___The lower your vitamin D level is, the higher your risk of death from ally cause will be. However, it's not a great idea to just take a supplement (补品) off the drugstore...
摘要: Provides information on the function of vitamin D. Information on the functions of the vitamin D hormone, 1,25-dihydroxyvitamin D by way of a nuclear receptor (vitamin D receptor, VDR); Binding of VDR to the direct repeat response elements called DR-3; What the binding requires....
Vitamin D status and related parameters in a healthy population: the effects of age, sex, and season. We conclude that in healthy individuals 1) compromised vitamin D status or serum 1,25-(OH)2D levels are not a normal concomitant of aging; 2) ......
The breakdown of the intestinal barrier is a common manifestation of many diseases. Recent evidence suggests that vitamin D and its receptor VDR may regulate intestinal barrier function. Claudin-2 is a tight junction protein that mediates paracellular water transport in intestinal epithelia, rendering ...
Vitamin D exerts its effects by binding to and activating the vitamin D receptor (VDR). Upon binding vitamin D, the VDR functions as a transcription factor, regulating the activity of over 1,000 different genes.[14] This “genomic” action of vitamin D tends to be slower-acting, requiring...
Vitamin D, either derived from the diet or skin production, has become an increasingly important molecule in human function because of the extended longevity of human populations in many nations. The actual vitamin D requirements of elderly individuals remain difficult to determine because environmental...