Cell membrane-based biovesicles (BVs) are important candidate drug delivery vehicles and comprise extracellular vesicles, virus-like particles, and lentiviral vectors. Here, we introduce a non-enzymatic assembly of purified BVs, supercharged proteins, an
Klatzmann, DavidExpert Review of VaccinesBellier B, Klatzmann D. Virus-like particle-based vaccines against hepatitis C virus infection[J]. Expert Rev Vaccines, 2013, 12 ( 2) : 143 -154.Bellier B., and Klatzmann D.: Virus-like particle-based vaccines against hepatitis C virus infection ...
Engineered virus-like particles for transient delivery of prime editor ribonucleoprotein complexes in vivo Meirui An, Aditya Raguram, Samuel W. Du, Samagya Banskota, Jessie R. Davis, Gregory A. Newby, Paul Z. Chen, Krzysztof Palczewski & David R. Liu Nature Biotechnology volume...
Based on their own electron microscopic studies and on those of David-Ferreira and Manaker (1965), Becker et al. (1967) considered that MHV might be an “IBV-like” (infectious bronchitis viruslike) agent. Virions of similar morphology seen in electron micrographs and also ether sens...
A putative mechanism of potyvirus particle movement through PD could be fueled by the ATPase activity of the CI protein. This mechanism would be similar to that proposed for the active transport of closterovirus particles, facilitated by Hsp70h, the viral chaperone-like ATPase present at their ...
Disassembly and reassembly of yeast-derived recombinant human papillomavirus virus-like particles (HPV VLPs) The human papillomavirus (HPV) virus-like particles (VLPs) produced by recombinant expression systems are promising candidate vaccine antigens for preventi... Henryk,Mach,David,... - 《Journal...
ORF2 encodes the only capsid protein, forming the virus particle, whose atomic structure has been solved recently [5]. HEV is one of the leading causes of human acute viral hepatitis in Asia, the Middle East and Africa. In industrialized countries, this virus has recently been recognized as ...
Engineered virus-like particles (eVLPs) are promising vehicles for transient delivery of proteins and RNAs, including gene editing agents. We report a system for the laboratory evolution of eVLPs that enables the discovery of eVLP variants with improved
This allows SARS-CoV-2 Virus-Like Particle (VLPs) formation composed of the viral structural proteins M, N, E and mature S. Furthermore, fluorescent or photoconvertible VLPs were generated by adding a fluorescent protein tag on N or M mixing with unlabeled viral proteins and characterized by ...
The present invention provides an Avian adeno-associated vims (AAAV) vims and vectors and particles derived therefrom. In addition, the present invention provides methods of deliver