病毒样颗粒(virus-like particle, VLP) 相关知识点: 试题来源: 解析 病毒样颗粒(VLP):用基因工程技术表达的HPV衣壳蛋白L1可在相应宿主细胞中组装成病毒样颗粒。VLP不含病毒核酸,其空间构象及免疫原性与天然HPV颗粒相似,刺激机体产生中和抗体。HPV VLP疫苗可用于HPV感染的预防。
乙型肝炎病毒(Hepatitis B Virus,HBV)VLP是第一个获得批准的基于VLP的疫苗,其次人类乳头状瘤病毒(Human Papilloma Virus,HPV)VLP和戊型肝炎病毒(Hepatitis E Virus,HEV)VLP相继被批准[1],2021年,疟疾疫苗被批准上市。除此之外,诺瓦克病毒VLP疫苗和流感病毒VLP疫苗正在进行临床试验,丙型肝炎病毒VLP疫苗和登革病毒VLP疫...
截至目前,公司已成功完成多个VLP疫苗项目检测,能够熟练掌握VLP颗粒质量标准及检测项目标准,积极助力VLP疫苗的快速发展。 参考文献 [1]Carvalho SB, Silva RJS, Sousa MFQ, Peixoto C, Roldão A, Carrondo MJT, Alves PM. Bioanalytics for Influenza Virus-Like Particle Characterization and Process Monitoring. F...
病毒样颗粒(virus-like particle, VLP)是由病毒衣壳蛋白(capsid protein, CP)自组装形成的球形或管状蛋白纳米结构,具有与天然病毒衣壳类似的结构,不含基因组、无感染性。近年来其在疫苗开发、药物靶向递送、生物医学成像与传感、组织工程等众多领域展现出独特的研究与应用价值。O网页链接 û收藏 转发 评论 ...
本发明公开了一种宫颈癌预防性VLP疫苗,VLP是HPV18型,52型,58型L1蛋白的环部位插入1个16型的E7表位而得到的嵌合蛋白的聚集体. The present invention discloses a cervical cancer preventive VLP vaccine, VLP is HPV18, 52, 58 type L1 protein inserted into a ring portion 16 of E7 epitopes resulting ...
virus-like-particle-VLP 例句 释义: 全部 更多例句筛选 1. Paramyxovirus structural proteins within a virus-like particle (VLP) comprise one example of such a vaccine. 病毒样颗粒(VLP)内的副粘病毒结构蛋白包含这种疫苗的一个实例。 ip.com© 2024 Microsoft 隐私声明和 Cookie 法律声明 广告 帮助 反馈...
泽润生物拥有重组病毒样颗粒(Virus Like-Particle,简称VLP)制备技术平台、重组蛋白表达技术平台、创新佐剂评估平台及灭活病毒疫苗研发技术平台。自主研发的重组人乳头瘤病毒双价(Human papillomavirus (HPV), 16/18型)疫苗已获得国家食品药品监督管理局颁发的药物临床试验批件,正在Ⅱ临床研究阶段,是国内第一家进入临床阶段...
Virus-like particle (VLP) is a nanostructure with self-assembly feature that contains structural proteins of virus. Molecular and morphological characteristics of VLP are similar to authentic viruses. Due to lack of genetic materials, VLP is not able to replicate or cause infection and does not re...
Vaccines based on virus-like particle (VLP) technology aim at harnessing the potent immunogenicity of natural viruses devoid of any hazardous infectious trait. VLPs result from the self-assembling of single or multiple viral capsid proteins and have been shown to be safe and efficacious in humans....
Virus-Like Particle (VLP) Products and Services Playing a critical role in virology research www.creative-biolabs.com | Contact Us Virus-Like Particle (VLP) Virus Like Particle Native Virus Virus-like particles (VLPs) are nanostructures that resemble the structure of viruses. VLPs represent ...