Learn the definition of the virulence factor. Discover virulence factor examples. Know about virulence factors of bacteria and virulence factors of...
By definition, a virulence factor is a gene product that enables a microorganism to establish itself on or within a host of a particular species and enhance its potential to cause disease. From: Advanced Drug Delivery Reviews, 2009 About this pageSet alert Also in subject areas: Chemistry Immun...
precursor, including the predicted protein having sequence simi- larity to previously identified TOMM precursors, hav- ing a suitable leader peptide cleavage motif and having a C‑terminal core region that is rich in heterocyclizable NATURE REVIEWS | MICROBIOLOGY © 2011 Macmillan Publishers ...
2.1What is virulence? Parasites per definition harm their hosts by decreasing their fitness (Read, 1994). This harm is referred to asvirulence, the prime factor describing parasites. Virulence is frequently measured as reduction in host reproduction, hostdeath rateor time to death, but any other...
Moreover, the virulence factor γ-haemolysin B (HIgB) of S. aureus bound to the AMFR and regulated TAB3. Our findings highlight an unknown role of AMFR in intracellular S. aureus infection-induced pneumonia and suggest that pharmacological interruption of AMFR-mediated TAB3 signalling cascades ...
Virulence and AMR genes were identified with abricate (v1.0.1) [51] using the virulence factor database (VFDB) [52], the comprehensive AMR database (CARD) [53], and a novel RTX toxin database (n = 1389), which was composed of RTX toxin and RTX toxin-related protein sequences...
Pathogenic leptospires are the bacterial agents of leptospirosis, which is an emerging zoonotic disease that affects both animals and humans worldwide. In this Review, the recent advances in our understanding of the epidemiology, taxonomy, genomics and t
proteins not typically expected in the secretome. For example, ATP subunits/carriers, translation elongation factor, actin, and multiple ribosomal proteins were identified and their presence was attributed to packaging in extracellular vesicles, and not necessarily due to direct secretion. In the absence...
theimmune systemstatus of the host is ultimately the determining factor that allows these fungi to cause disease. This fact alone strongly suggests that the majority of human fungal pathogens have not evolved specificvirulence factorsin the classic definition of the term. Instead, certain fungi have...
Fig. 1. Modes of bacterial virulence factor entry into host cells. (a) Pathogenic bacteria, such as Vibrio cholera, secrete toxins into the extracellular milieu, which then enter host cells. Cholera toxin is depicted in orange. (b) Other extracellular bacteria, such as EPEC, bind to host ce...