Variation in Chromosome Structure and NumberBrooker, Rob
This is Figure X, la and b' Chromosome Y1 and Y2 arrowed complements of Rumex acetosa (a) 9, 2n = 14+1 B; X-chromosomes arrowed. (b) d, 2n = 15 + 2Bs; 'lIar in all figures represents 10 p.m. V-CHROMOSOME STRUCTURE OF RUMEX ACETOSA 249 (b) Y-chromosomes In conventionally...
Chromosome conformation capture (3C). PCR-based proximity-ligation analysis method of 3D genome organization that allows a reconstruction of the native chromatin structure within the nucleus. 3C employs a PCR-based approach to confirm interactions between two previously known loci (one versus one). Th...
Changes in the overall structure of chromatin are essential for the proper regulation of cellular processes, including gene activation and silencing, DNA repair, chromosome segregation during mitosis and meiosis, X chromosome inactivation in female mammals, and chromatin compaction during apoptosis. Such ...
Summary Eleven biallelic polymorphisms and seven short-tandem-repeat (STR) loci mapping on the nonrecombining portion of the human Y chromosome have been typed in men from northwestern Africa. Analysis of the biallelic markers, which represent probable unique events in human evolution, allowed us to...
The yeast chromosome may be a model of the structure of the human genome, since there is evidence that it is also a mosaic of long regions of different base compositions, reflected in wide variation of G+C content at silent sites among genes. Two possible causes of this regional effect, ...
Notably, the most common somatic alteration in PCa involves an intrachromosomal translocation or 3Mb deletion on chromosome 21, resulting in fusion of the androgen-responsive gene TMPRSS2 and members of the E26 transformation-specific (ETS) transcription factor family [9]. TMPRSS2-ERG gene ...
The importance of SV to gene expression (direct and indirect) [32], protein structure [33], and chromosome stability [34, 35] is being increasingly recognized in normal development and disease [9, 20]. At the same time we show that SVs are: 1, grossly under-represented in published NGS...
In chromosome terms White (1973) has discussed this under the heading of Karyotypic Orthoselection, where lineages show recurrent classes of chromosome changes during evolution. The chromosome structure of natural popula- tions of the dioecious flowering plant Rumex acetosa has recently been ...
N. et al. Chromosome-scale scaffolding of de novo genome assemblies based on chromatin interactions. Nat. Biotechnol. 31, 1119–1125 (2013). CAS PubMed PubMed Central Google Scholar Steininger, A. et al. Genome-wide analysis of interchromosomal interaction probabilities reveals chained ...