The random fluctuation of allele frequencies in a population due to chance variations in the contribution of each individual to the next generation. Deep-rooting Describes a human pedigree that contains the descendants of common ancestors who lived several or many generations ago. Bayesian skyline plo...
2006 The pattern of chromosome-specific variations in telomere length in humans shows signs of heritability and is maintained through life. Ann. N. Y. Acad. Sci. 1067, 311-316. (doi:10.1196/annals.1354.042)Graakjaer, J., London˜ o-Vallejo, J., Christensen, K. and Kolvraa, S. (...
17,19,20. Nature has evolved numerous variations to this generally accepted theory of sex chromosome evolution and sex determination. For example, neo-sex chromosomes can also evolve in situations where a sex chromosome pair already exists, either by fusion to an autosome or by acquisition of a ...
Sex chromosome, either of a pair of chromosomes that determine whether an individual is male or female. The sex chromosomes of human beings and other mammals are designated by scientists as X and Y. In humans the sex chromosomes consist of one pair of th
As one example, cytogenetic banding greatly increased the ability to detect structural variations in chromosomes. If a detectable variation was associated with a specific disorder, for example deletion of 15q11-13, then the suspected phenotype of Prader–Willi syndrome (PWS) in a patient was confirm...
Differences in male vs. female immune responses are well-documented and have significant clinical implications. While the immunomodulatory effects of sex hormones are well established, the contributions of sex chromosome complement (XX vs. XY) and gut mi
Associated Repeats) but these regions, rather than being highly conserved, are highly polymorphic - that is they have many variations even within the same species. Nevertheless the pretelomeric region can be easily recognised in closely related species. Occasionally genes are found in the pre...
When a locus by locus AMOVA was performed in the Mediterranean group, only three out of 25 markers showed significant (p < 0.05) variations among the Mediterranean populations (X029, X062, and X121), while 17 out of 21 markers were important for the differentiation of the 9 "worldwide" ...
展开 关键词: Humans Cell Line Leukemia Gene Expression Profiling Genetic Heterogeneity DNA Replication Timing Epigenesis, Genetic Child DNA Copy Number Variations Precursor Cell Lymphoblastic Leukemia-Lymphoma DOI: 10.1101/gr.133751.111 被引量: 146 年份: 2012 收藏...
Neurodevelopmental variability in three young girls with a rare chromosomal disorder, 48, XXXX X and Y chromosome variationsaneuploidychildhood apraxia of speechsex chromosomestetrasomy XFourty eight, XXXX is a rare chromosomal aneuploidy associated with ... SS Carole,K Colleen,M Francie,... - 《Ame...