Reynolds,PE.Studies on the mode of action of vancomycin.Biochimica et Biophysica Acta. 1961Reynolds, P. E. 1961. Studies on the mode of action of vancomycin. Biochim. Biophys. Acta 52:403-405.Reynolds PE (1961) Studies on the mode of action of vancomycin. Biochim Biophys Acta 52:403–...
[1]. Rybak MJ, et al. The pharmacokinetic and pharmacodynamic properties of vancomycin. Clin Infect Dis. 2006 Jan 1;42 Suppl 1:S35-9. [2]. Watanakunakorn C, et al. Mode of action and in-vitro activity of vancomycin. J Antimicrob Chemother. 1984 Dec;14 Suppl D:7-18. ...
参考文献: [1]. Rybak MJ, et al. The pharmacokinetic and pharmacodynamic properties of vancomycin. Clin Infect Dis. 2006 Jan 1;42 Suppl 1:S35-9. [2]. Watanakunakorn C, et al. Mode of action and in-vitro activity of vancomycin. J Antimicrob Chemother. 1984 Dec;14 Suppl D:7-18. [3...
Mode of action and in-vitro activity of vancomycin. J Antimicrob Chemother. 1984 Dec;14 Suppl D:7-18.Warren CA, et al. Vancomycin treatment's association with delayed intestinal tissue injury, clostridial overgrowth, and recurrence of Clostridium difficile infection in mice. Antimicrob Agents ...
Mode of action: interferes with cell wall synthesis Antimicrobial spectrum: Gram-positive bacteria Other Notes Studies on bond strength in vancomycin-peptide complexes.1 Structure of vancomycin and its complex with acetyl-D-alanyl-D-alanine.2
Vancomycin is an important antibiotic for the treatment of severe Gram-positive infection, especially in cases with resistant organisms or when the patient is allergic to penicillin. Because of its mode of action, pharmacokinetics and side effects, close liaison with the medical microbiologist is neces...
Mode of action The mechanism of action of this antimicrobial agent is via the inhibition of bacterial cell wall biosynthesis or, more specifically, the inhibition of peptidoglycan biosynthesis. It is, therefore, bactericidal for reproductive bacteria[1]. The bacterial cell wall contains peptidoglycan th...
Mode of action Resistance issue Side effects ReferencesVancomycin structure CAS No. 1404-90-6 Chemical Name: Vancomycin Synonyms Vancomycin Base;Vancomycin (base and/or unspecified salts);VANCOMYCIN;Vancomycin D12;Vancomycin D10;Vancomycin D13;Vancomycin USP/EP/BP;Vancomycin Impurity 21;vancomycin hc...
Mode of action: interferes with cell wall synthesis Antimicrobial spectrum: Gram-positive bacteria Other Notes Studies on bond strength in vancomycin-peptide complexes.1 Structure of vancomycin and its complex with acetyl-D-alanyl-D-alanine.2 性质 potency ≥900 μg per mg (as vancomycin base) ...
2、ycin is a large glycopeptide compound with a molecular weight of 1450 Da 1. Vancomycin is aunique glycopeptide structurally unrelated to any currently available antibiotic. It also has a unique mode ofaction inhibiting the second stage of cell wall synthesis of susceptible bacteria. Vancomycin ...