Introduction:Vancomycin dosing decisions are informed by factors such as body weight and renal function. It is important to understand the impact of obesity on vancomycin pharmacokinetics and how this may influence dosing decisions. Vancomycin dosing guidelines use varied descriptors of body weight and ...
Clinical practice guidelines by the Infectious Diseases Society of America for the treatment of methicillin-resistant SStaphylococcusaureus infection in adults and children. Clin Infect Dis. 2011;52(3):1–38. Article Google Scholar Le J, Bradley JS, Murray W, et al. Improved Vancomycin dosing ...
The initial vancomycin maintenance dosage for such patients should be 7.5–10 mg/kg every 12 hours. Consult the guidelines for additional information ([Web])Geriatric PatientsCautious dosage selection (usually starting at the low end of the dosing range) because of age-related decreases in renal ...
Stephen E. Harding Scientific Reports10, Article number:960(2020)Cite this article 9712Accesses 27Citations 18Altmetric Metrics
the use of actual body weight is recommended for dosing in vancomycin regimen designs, and it is important to perform therapeutic drug monitoring for effica... Sakurai, Norihiro,Kawaguchi, Hiroshi,Kuwabara, Gaku,... - Chemotherapy (0009-3157) 被引量: 0发表: 2022年 Therapeutic Drug Monitoring-...
Join Wolters Kluwer as they showcase how Sentri7, with the redesigned DoseMeRx, empowers pharmacists to overcome the challenges of vancomycin dosing, streamlines pharmacy workflow, and improves patient outcomes at ajoint webinaron June 15, 2022 at 12pm CST. ...
S. aureus strains that have reduced vancomycin susceptibility based on standard laboratory susceptibility testing methodology. A better understanding is still needed of the pharmacodynamic relationship between vancomycin and MRSA as relates to optimal dosing strategies, including consideration of loading doses...
·mL-1,the AKI rates are 15.8%,20.5%,25.8%,and 39.4%,respectively.Multivariate logistic regression analysis showed that target concentrations were more likely to be reached with a dosing course of >7-14 d (OR=1.688,P=0.001) and >14 d (OR=1.744,P=0.002) than with a dosing course of ...
Vancomycin, a glycopeptide antibiotic, has the potential to cause severe nephrotoxicity and ototoxicity. Historically, vancomycin dosing has been titrated to obtain serum trough concentrations of 10 to 15 mg/L for infections and 15 to 20 mg/L for severe infections, such as bacterial meningitis7,8...
increase efficacy and minimize harm in other antibiotic classes33. Recent studies showed that under-dosing and over-dosing in selected patient groups, such as critically-ill, elderly, burn patients and severely obese patients, occurs also with standard dosing of beta-lactam antibiotics34. Pea et ...