Vancomycin Dosing, Monitoring and Toxicity: Critical review of the clinical practiceacute kidney injuryefficacynephrotoxicitypharmacodynamicspharmacokineticssafetysepsisvancomycinVancomycin is an antibiotic used in the treatment of infections caused by multidrug‐resistant Gram﹑ositive bacteria, especially methicillin...
Article CAS PubMed PubMed Central Google Scholar van Hal S, Paterson D, Lodise T. Systematic review and Meta-analysis of Vancomycin-Induced Nephrotoxicity Associated with Dosing schedules that maintain troughs between 15 and 20 milligrams per Liter. Antimicrob Agents Chemother. 2012;57(2):734–...
A Systematic Review of Vancomycin Dosing and Monitoring in Burn Patientsdoi:10.1097/BCR.0000000000000191vancomycinadultburnspediatricstrough concentrationVancomycin pharmacokinetics are significantly altered following burn injury, requiring a higher total daily dose to achieve adequate serum concentrations. Wide ...
Vancomycin dosing is based on population pharmacokinetic parameters without using individual patient pharmacokinetic results. Several nomograms have been developed to empirically dose vancomycin. Only one nomogram was validated in patients...
Background: In 2009, the American Society of Health System Pharmacists (ASHSP), Infectious Diseases Society of America (IDSA) and Society of the Infectious Diseases Pharmacists (SI DP) released a consensus statement on vancomycin dosing and monitoring. The appropriateness of these guidelines for a ...
have been well documented in the review article byCetinkaya et al. in 2000.Vancomycin resistanceis mediated by gene clusters or individual genes, giving rise to five phenotypes designated Van A, B, C, D, and E. Van A and B are widespread and exhibit the highest vancomycin meaninhibit...
Cited in this article [1] [6] RYBAKM,LOMAESTROB,ROTSCHAFERJ C, et al. Therapeutic monitoring of vancomycin in adult patients:a consensus review of the American Society of Health-System Pharmacists,the Infectious Diseases Society of America,and the Society of Infectious Diseases Pharmacists[J]....
Vancomycin, a branched tricyclic glycosylated peptide antibiotic, is a last-line defence against serious infections caused by staphylococci, enterococci and other Gram-positive bacteria. Orally-administered vancomycin is the drug of choice to treat pseud
This was due to improved survival among patients treated with vancomycin, which may have been due to greater attention paid to vancomycin dosing during the study period or because of the use of salvage therapy with linezolid in patients in the vancomycin arm. Thus, despite the lack of a ...
Prospective trial on the use of trough concentration versus area under the curve to determine therapeutic vancomycin dosing. Antimicrob Agents Chemother. 2018;62(2):e02042-e02017.PubMedGoogle Scholar Combination Therapy for MRSA Bacteremia—Not Ready for Prime Time JAMA Editorial February 11, 2020...