Optimizing Vancomycin Dosing for Peri-operative Prophylaxis in High-risk Orthopedic Surgery Patients: Time for A ChangeMarco R. Scipione, PharmD
However, routine use of vancomycin for antimicrobial surgical prophylaxis is not recommended since such use may promote emergence of vancomycin-resistant enterococci or staphylococci.The American Society of Health-System Pharmacists (ASHP), Infectious Diseases Society of America (IDSA), Surgical Infection ...
Prophylaxis of infection in cardiac, thoracic, and arterial procedures; craniotomy; joint replacement; amputation 15 mg/kg IV over 1-2 hours; begin administration within 2 hours before incision; duration of prophylaxis for most procedures should be less than 24 hours Dosing Modifications Renal impairm...