A Series of articles from Nature Reviews Cardiology on valvular heart diseases, including mitral valve, tricuspid valve and aortic valve disease, discussing the latest findings on mechanisms, diagnosis and management
VHD (stenosis, insufficiency, or combined lesions) is a major class of heart disease; if severe and left untreated, it may lead to irreversible myocardial damage and death. VHD may exert its deleterious effect both by a direct decrease of stroke volume (e.g., with critical AS or acute ...
3.6 Valvular heart disease Valvular heart disease (VHD) is a structural or functional abnormality of cardiac valves. The main causes of VHD are calcific aortic stenosis in the elderly, floppy mitral valve/mitral valve prolapse associated with mitral regurgitation, bicuspid aortic valve, VHD asso...
Valvular heart disease (VHD) is a major contributor to loss of physical function, quality of life and longevity. The epidemiology of VHD varies substantially around the world, with a predominance of functional and degenerative disease in high-income countries, and a predominance of rheumatic heart ...
With this aging population, the prevalence of valvular heart disease (VHD) is on the rise. The etiology, approach to treatment, and expected outcomes of VHD are different in the elderly compared with younger patients. Both stenotic and regurgitant lesions are associated with unfavorable outcomes...
Valvular heart disease (VHD) is caused by either damage or defect in one of the four heart valves, aortic, mitral, tricuspid or pulmonary. Defects in these valves can be congenital or acquired. Age, gender, tobacco use, hypercholesterolemia, hypertension, and type II diabetes contribute to the...
Given the shared pathways between several cardiovascular conditions, it has been suggested that elevated blood pressure (BP) increases the risk of VHD as it does with stroke or ischemic heart disease.5 Initial supportive evidence for this hypothesis came from cross-sectional studies showing a positive...
Background: Valvular heart disease (VHD) is expected to cause an increase in public-health problems in the coming years, especially in elderly populations. We aim to estimate the incidence, mortality, and burden of VHD, by age, from 1990 to 2017 in 195 countries and territories. Methods: We...
Given the shared pathways between several cardiovascular conditions, it has been suggested that elevated blood pressure (BP) increases the risk of VHD as it does with stroke or ischemic heart disease.5 Initial supportive evidence for this hypothesis came from cross-sectional studies showing a positive...
(VHD). Prevalence increases markedly after age 65. Patients with mild or moderate VHD, and somepatientswith severe VHD, may have no symptoms and be unaware of their disease. Severe VHD leads to deterioration of the heart's function, which can cause shortness of breath, chest pain, ...