Valproic acid serum levels were within limits, hepatic function tests were normal but ammonia levels were above the normal range.Valproic acid was stopped and the hyperammonemic encephalopathy was treated with lactulose 15ml twice daily, metronidazole 250mg four times daily and L-carnitine 1g twice ...
doi:10.1080/j.1440-1614.2006.01892.xLETTERSPSYCHIATRYA letter is presented in response to an article on polydipsia published in a previous issue of the periodical.Australian & New Zealand Journal of PsychiatryGuaiana, GiuseppeEyrek, CetinMariconda, Giuseppe...
One trial evaluated 48 clinic visits for acute migraine attack in 31 patients; adequate pain relief was reported in 77.6% of visits (n=45) after a single valproic acid dose; the mean time to achieve maximum pain relief was 63 ± 31 minutes (range: 15 to 160 minutes) after a single ...
Valproic acid serum levels were within limits, hepatic function tests were normal but ammonia levels were above the normal range. Valproic acid was stopped and the hyperammonemic encephalopathy was treated with lactulose 15 ml twice daily, metronidazole 250 mg four times daily and L-carnitine ...
Objective To investigate the radioprotective effects of valproic acid( VPA),an antiepileptic drug,on the normal brain tissues of rats. Methods A total of 48 male Wistar rats were randomized into VPA group,radiotherapy group...
药物别名 2-n-propyl-n-valeric acid;2-propyl-pentanoic acid;2-Propylpentanoic Acid;2-Propylvaleric Acid;4-heptanecarboxylic acid;acide valproïque;ácido valproico;acidum valproicum;di-n-propylacetic acid;Di-n-propylessigsäure;Dipropylacetic acid;DPA;n-DPA;Valproate;Valproic acid;Valproinsä...
Surprisingly, despite years of research,valproic acid'smechanism of action has remained unclear. Here, we have provided insight into valproic acid's putative mechanism of action. Further, we used a simple model system,Dictyostelium, to screen a range of medium-chain fatty acids and their derivativ...
STAVZOR (valproic acid) delayed release capsules are administered orally, and must be swallowed whole. The recommended initial dose is 750 mg daily in divided doses. The dose should be increased as rapidly as possible to achieve the lowest therapeutic dose which produces the desired clinical effec...
With regard to blood coagulation, we found that at various time points (3–24 months) of long-term VPA monotherapy, the PLT counts significantly decreased but remained within the normal range. In addition, there was no significant difference in the incidence of nasal bleeding between the short-...
Valproic acid is a commonly used anti-epileptic drug. Hematological toxicities are among the occasionally observed adverse effects of this medication. We present the case of a 13-year-old Caucasian boy who demonstrated mild anemia 12 months after the