Vagus nerve stimulation has entered the clinic and yet its fundamental basis is poorly understood. The present study was designed to evaluate whether supramedullary neurons contributed to neuronal activity in NTS during VNS treatment. Thus, we hypothesized that supramedullary neurons were activated by ...
Vagus nerve stimulation (VNS) for treatment of heart failure (HF) showed promise in preclinical experiments (Li et al.2004; Sabbah et al.2005), but subsequent clinical studies failed to meet efficacy endpoints (De Ferrari et al.2014; Gold et al.2016). A potential contributor to this discrep...
The left side is chosen to avoid unwanted vagal stimulation of the heart, because the majority of efferent fibers to the heart travel along the right vagal nerve. However, small studies have shown that right vagus nerve stimulation is safe and effective.70–72 The platysma is divided and ...
Vagus nerve stimulation (VNS) offers a promising therapy due to its anti-inflammatory effects. Its invasive nature, however, has led to the development of non-invasive methods like transcutaneous auricular VNS (taVNS). This study assesses taVNS's impact on acute colitis progression, inflammatory...
Vagus-nerve stimulation, acetylcholine and nicotine inhibit the production of pro-inflammatory cytokines from macrophages through a 'nicotinic anti-inflammatory pathway' that is dependent on the α7 nicotinic acetylcholine receptor (α7nAChR). Similar to the development of α- and β-agonists for adren...
Relationships were examined between outflows of the lumbar colonic nerve (LCN) and rectal branch of the pelvic nerve (RB) and distal colonic motility (DCM) during proximal colonic distension in anesthetized and decerebrate dogs. Distensi... K Fukai - 《Kawasaki Medical Journal》 被引量: 2发表...
The aim of the present study was to explore the mechanisms of these therapies against 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced colitis in rats using a chronic vagus nerve stimulation model in vivo, as well as the lipopolysaccharide (LPS)-induced inflammatory response in human epithelial...
Article: Actions of putative transmitters in the chicken vagus nerve/oesophagus and Remak nerve/rectum preparations
Systemic lipopolysaccharide influences rectal sensitivity in rats: role of mast cells, cytokines, and vagus nerve. Am J Physiol Gastrointest Liver Physiol 2000;279:G781-90.Coelho AM, Fioramonti J, Bueno L. Systemic lipopolysaccharide influences rectal sensitivity in rats: role of mast cells, ...
Rectal evacuation was produced by intermittent MS. MS activates not only the muscles but also the nervous tissue. In the present study I investigated the effect of MS of the vagus nerve on the colonic transit to evaluate the possibility of using this method in the treatment of constipation due...