A homogeneousLactobacillus-dominated microbiome has long been considered the hallmark of health in the female reproductive tract. In contrast, a vaginal microbiome with high species diversity, as observed with bacterial vaginosis, has been associated with increased risk for acquisition and transmission of ...
Purpose: Preterm birth (PTB) is a major cause of neonatal mortality. The vaginal microbiome is associated with PTB, but results vary across racial/ethnic populations. Some evidence suggests gestational age affects this association. We investigated these associations in a novel population, conducting a...
vaginal microbiomerace/ethnicityReproductive tract infection is a major initiator of preterm birth (PTB). The objective of this prospective cohort study of 88 participants was to determine whether PTB correlates with the vaginal microbiome during pregnancy. Total DNA was purified from posterior vaginal ...
M. et al. The vaginal microbiome and preterm birth. Nat. Med. https://doi.org/10.1038/s41591-019-0450-2 (2019). Article CAS PubMed PubMed Central Google Scholar Shah, R. et al. Incidence and risk factors of preterm birth in a rural Bangladeshi cohort. BMC Pediatr. 14, 112 (...
Researchers in the UK recently discovered a rapid test that checks the vaginal microbiome and can detect risks of preterm birth. Usually, tests to check the microbiome are complicated and it takes a long time to get a result.
Regarding the genital tract microbiome, population nucleotide diversity, selection metrics, and antibiotic resistance potential are associated with preterm birth [17]. This study offers a unique population genetic elucidation of the association between the vaginal microbiome and alterations in the host envir...
during pregnancy has been re- ported to be associated with many complications of pregnancy, such as an increased risk of miscarriage, preterm birth and endometritis [18, 21, 22], yet few studies have investigated the relationship between HPV infection and the vaginal microbiome in preg- nant ...
Over 30% of people with vaginas have an imbalanced vaginal microbiome, which can manifest as BV, yeast infections, recurrent UTIs, and more. The latest research has also uncovered links between the vaginal microbiome and critical outcomes, such as infertility, STIs, preterm birth, and more. ...
M. et al. The vaginal microbiome and preterm birth. Nat. Med. 25, 1012–1021 (2019). Ding, T. & Schloss, P. D. Dynamics and associations of microbial community types across the human body. Nature 509, 357–360 (2014). Article ADS CAS PubMed PubMed Central Google Scholar Friedman,...
Direct on-swab metabolic profiling of vaginal microbiome host interactions during pregnancy and preterm birth ArticleOpen access13 October 2021 Main Preterm birth (PTB), childbirth before 37 weeks of gestation, is the leading cause of neonatal death, and may lead to a variety of lifelong morbidit...