Cold-adapted, live, attenuated, trivalent, intranasal influenza vaccine (CAIV-T) is well accepted, well-tolerated, highly protective against culture-confirmed influenza, and provides significant health benefits to children and adults. A 2-year, multicenter, double-blind, placebo-controlled efficacy ...
to a vaccine administered under field conditions to a given population[1,3,6,12]. It is measured by observational post-licensure studies. It can thus be clearly distinguished fromvaccine efficacy[3,10,13]. Bothvaccine efficacyand effectiveness (VE) are measured according to the following formula...
Vaccine epidemiology: Efficacy, effectiveness, and the translational research roadmap. Journal of Infectious Diseases, 201(11), 1607-1610... Weinberg,Geoffrey,A.,... - 《Journal of Infectious Diseases》 被引量: 117发表: 2010年 Association between the Asp299Gly Polymorphisms in the Toll-like Rec...
There have been a few published systematic reviews of efficacy/effectiveness and/or safety of some of the enhanced vaccines [17, 82,83,84]. Based on a recent comprehensive systematic review that compared the enhanced vaccines with the traditional vaccines in subjects aged ≥18 years irrespective ...
VE and GD distributions by vaccine platform VE and GD of the four vaccine platforms with authorized use are compared in Fig.1. Within each vaccine platform, the vaccine effectiveness is generally lower compared to the efficacy outcome (Fig.1a), whereas, in terms of genetic mismatch (Fig.1band...
Table 1 Data sources for efficacy data Full size table Figure2presents the aggregated data on vaccine effectiveness in preventing severe COVID-19 for different vaccines, variants and time since vaccination. These are key parameters of interest, as they have each been shown to independently influence...
The Sinovac vaccine is 67 percent effective in preventing symptomatic infection and 80 percent effective in fending off deaths from the disease, according to a report released on Friday by Chile's Ministry of Health. A report on the efficacy of the vaccine known as CoronaVac ...
A recent methodological study indicated that no systematic review has been published thus far on the efficacy, effectiveness, and safety of seasonal influenza vaccination in patients with ESRD receiving dialysis [17]. We therefore performed a respective systematic review and meta-analysis and used the...
One showed an effectiveness of 90% when trial participants received a half dose, followed by a full dose at least one month apart. The other dosing regimen showed 62% efficacy when given as two full doses at least one month apart. Pascal Soriot, CEO of AstraZeneca, said the development ...
Additional studies are needed to determine methods for improving the efficacy of the vaccine and the effectiveness of the influenza vaccination program in preventing influenza infections in the United States. 展开 关键词: Humans Lung Diseases Chronic Disease Exercise Test Forced Expiratory Flow Rates ...