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Gene Rearrangement, gamma-Chain T-Cell Antigen ReceptorMonoclonal antibodies (mAb) were used to characterize a panel ( n = 46) of T cell receptor (TcR) /+ T cell clones. Three of these antibodies have been described to react with specific variable region-encoded protein products and can ...
They are implicated in processes like bone remodeling [313,314], production of hormones [315], as well as the presentation of antigens in the immune system [316]. Due to the acidic extracellular tumor microenvironment, cysteine cathepsins are able to function in proteolytic pathways that promote...
et al. Individual heritable differences result in unique cell lymphocyte receptor repertoires of naive and antigen-experienced cells. Nat. Commun. 7, 11112 (2016). 18. Wang, Y. et al. Genomic screening by 454 pyrosequencing identifies a new human IGHV gene and sixteen other new IGHV allelic ...
type I has been linked to CTCL (Pancake et al, 1995), and this potentially could account for the findings by immunoscopy, it seems possible that sustained superantigenic stimulation of sensitive T cell populations by a microbial antigen might also cause depletion of such cells in the blood. ...
A human endogenous retroviral superantigen as candidate autoimmune gene in type I diabetes Cell, 90 (1997), pp. 303-313 View in ScopusGoogle Scholar [15] H. Perron, E. Jouvin-Marche, M. Michel, A. Ounanian-Paraz, S. Camelo, A. Dumon, C. Jolivet-Reynaud, F. Marcel, Y. Souillet...
The presence of heterogeneity in responses to oncolytic virotherapy poses a barrier to clinical effectiveness, as resistance to this treatment can occur through the inhibition of viral spread within the tumor, potentially leading to treatment failures. Here we show that 4-octyl itaconate (4-OI), ...