In addition, mechanisms such as mutagenic repair or dimer bypass, recombinational repair, cell-cycle checkpoints, apoptosis and certain alternative repair pathways are also operative in various organisms. This review deals with UV-induced DNA damage and the associated repair mechanisms as well as ...
UV-induced DNA damage and repair: a review Increases in ultraviolet radiation at the Earth's surface due to the depletion of the stratospheric ozone layer have recently fuelled interest in the mecha... RP Sinha,H?der, Donat-P. - 《Photochemical & Photobiological Sciences Official Journal of ...
Frank R de Gruijl aHenk J van Kranen cLeon H.F Mullenders bElsevier B.V.J Photochem Photobiol Bde Gruijl FR, van Kranen HJ, Mullenders LH (2001) UV-induced DNA damage, repair, mutations and oncogenic pathways in skin cancer. J Photochem Photobiol B 63: 19-27....
Constant κ and μ genes when irradiated as part of the chromatin of living lymphocytes showed a UV sensitivity similar to that of naked DNA. The same genes from granulocytes had 50–60 times lower UV sensitivity. When cells were allowed to repair photolesions for 24 h the facultative bands ...
Ultraviolet (UV) radiation is a carcinogen that generates DNA lesions. Here, we demonstrate an unexpected role for DGCR8, an RNA binding protein that canonically functions with Drosha to mediate microRNA processing, in the repair of UV-induced DNA lesions. Treatment with UV induced phosphorylation ...
UV-B-induced DNA damage mediates expression changes of cell cycle regulatory genes in Arabidopsis root tips. Planta 233, 831–841. Kakani VG, Reddy KR, Zhao D, Sailaja K (2003). Field crop responses to ultraviolet-B radiation: a review. Agric For Meteorol 120, 191–218. Kataria S, ...
Molecular response to climate change: temperature dependence of UV-induced DNA damage and repair in the freshwater crustacean Daphnia pulicaria. Glob. Chang. Biol. 10, 408-416.MacFadyen EJ, Williamson CE, Grad G, Lowery M, Jeffrey WH, Mitchell DL. Molecular response to climate change: ...
Nucleotide excision repair hotspots of UV-induced DNA damage in the human genomeThe ERCC1-XPF heterodimer is a structure-specific endonuclease and plays multiple roles in various DNA repair pathways including nucleotide excision repair and also telomere maintenance. The dimer formation, which is ...
The widespread occurrence of this enzyme capable of repairing sunlight-induced damage to DNA justifies continued research efforts to uncover not only the molecular basis for its action, but also its ecological significance. The enzyme is unique in that it is the only one known that has an ...
The p127 subunit (DDB1) of the UV-DNA damage repair binding protein is essential for the targeted degradation of STAT1 by the V protein of the paramyxoviru... 2002. The p127 subunit (DDB1) of the UV-DNA damage repair binding protein is essential for the targeted degradation of STAT1 ...