SynonymsSunlight damage to DNA; UV damage to DNASynopsisSunlight is healthy and necessary in vitamin D activation, but it is also a major cause of skin cancer. UV light causes the formation of several DNA adducts, of which the most serious ones are cyclobutane dimers and pyrimidine-pyrimidone ...
The shorter wavelength UV-C light carries with it significantly more energy than its long wave UV-A counterpart, and is much more damaging to DNA. This increased capacity for DNA damage of UV-C is also because DNA absorbs light at a maximum of 260 nm, which is within the UV-C range. ...
13. VOCs (Volatile Organic Compounds) -挥发性有机化合物 14. UV (Ultraviolet) -紫外线 15. LED (Light Emitting Diode) -发光二极管 16. Cure - 固化 17. DNA damage -DNA损害 18. Mutation - 突变 19. Epidemiological study -流行病学研究 20. Ventilation - 通风 背单词有困难,可以用公益记忆方法...
DNA damage appears to be a fundamental problem for life. In this chapter we review evidence indicating that DNA damages are a major primary cause of cancer. DNA damages give rise to mutations and epimutations that, by a process of natural selection, can cause progression to cancer. First, we...
DNA损伤(DNA damage):DNA组成与结构变化;突变(Mutation):DNA碱基对的改变。DNA damage is not the same as mutation, although it can lead to mutation.可以导致突变的DNA损伤称为遗传毒性的(Genotoxic)损伤。 1 DNA损伤 DNA损伤有多种类型: 碱基损伤与糖基破坏; ...
(NER). A DNA repair pathway that recognizes and removes bulky DNA lesions such as those formed by UV light. NER involves damage recognition, nicks flanking the lesion and removal of the damaged DNA strand, filling in the gap by DNA polymerase and ligation of the nicks to restore the intact...
DNA损伤(DNA damage):DNA组成与结构变化;突变(Mutation):DNA碱基对的改变。DNA damage is not the same as mutation, although it can lead to mutation.可以导致突变的DNA损伤称为遗传毒性的(Genotoxic)损伤。 1 DNA损伤 DNA损伤有多种类型: 碱基损伤与糖基破坏; ...
the action of different recruited BER proteins, including DNA polymerases, poly [ADP-ribose] polymerase 1 (PARP1) and DNA ligases. The NER mechanism frequently repairs other forms of DNA damage, including pyrimidine dimers (such as T = T), which are commonly caused by UV light exposure...
DNA damage in the sperm can be induced by six mechanisms: (1) apoptosis during spermatogenesis; (2) DNA strand breaks during sperm chromatin remodeling; (3) posttesticular DNA fragmentation caused by oxygen radicals; (4) DNA fragmentation induced by endogenouscaspases; (5) radiotherapy and chemoth...
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