Parkinson's disease (PD) is the second most common neurodegenerative disease in the world. Identification of PD biomarkers is crucial for early diagnosis and to develop target-based therapeutic agents. Integrative analysis of genome-scale metabolic model
In unimpaired adults, Hybrid-SINDy automatically identified spring-loaded inverted pendulum-like template signatures, which did not change with exoskeletons (p > 0.16), except for small changes in leg resting length (p < 0.001). Conversely, post-stroke paretic-leg rotary stiffness ...
Structural equation modeling (SEM), which is rarely used in green space research, may serve as an alternative, capturing multiple regression equations simultaneously (Hair. et al., 2014). The present research addressed these research gaps by examining residential green space–mental health pathways ...
In the figure below, the graphs titled “KDM Biological Age” and “Levine Phenotypic Age” show measures based on the original biomarker sets published in Levine 2013 J Geron A and Levine et al. 2018 AGING. The remaining graphs shows the new measures computed with the biomarker set specified...
which included the delta position of acceptor gain (DP_AG), acceptor loss (DP_AL), donor gain (DP_DG), and donor loss (DP_DL). SpliceAI does not annotate variants if they are close to chromosome ends or too long reference sequences. We use 0 to fill in missing values of SpliceAI ...
in child led activities across everyday environments. Researchers have provided training in naturalistic teaching via a telehealth platform to train both parents and professionals (Craig et al.,2021; Neely et al.,2019; Vismara et al.,2009; Wainer et al.,2017), with the majority of studies ...
4 industry mapping reference. [Data set]. https://development-data-hub-s3-public.s3.amazonaws.com/ddhfiles/144635/linkedin_to_isic_rev_4_industry_mapping_0.csv World Bank Group (2020) GDP per capita, PPP (current international dollars) [Data set]. http://api.worldbank.org/v2/en/...
Significant challenges remain in the computational processing of data from liquid chomratography-mass spectrometry (LC-MS)-based metabolomic experiments into metabolite features. In this study, we examine the issues of provenance and reproducibility usin
Since emergence of the initial SARS-CoV-2 BA.1, BA.2 and BA.5 variants, Omicron has diversified substantially. Antigenic characterization of these new variants is important to analyze their potential immune escape from population immunity and implication
Ultimately, this study aims to provide a new fit-for-purpose complementary analytical approach to assess the quality of complex botanicals and derived formulations, to enable more rapid advances in the regulatory context. Methods Botanical formulations and reference material ...