BOTPPI, a New Wittig Salt Used in the Synthesis of 12-(S)-Hydroxy-Eicosatetraenoic Acid [12-(S)- HETE] BOTPPI, a new Wittig salt for the synthesis of 12-(S) -hydroxy-eicosatetraenoic acid [12-(S)-HETE]M A ChristiansenMerritt B Andrus...
15(R)-hydroxyeicosatetraenoic acid 17R-HDHA 17R-hydroxydocosahexaenoic acid 18R-HETE 18R-hydroxyeicosapentaenoic acid 5-LOX 5-lipoxygenase AA arachidonic acid ABPM ambulatory blood pressure measurement ACEI angiotensin-converting enzyme inhibitors
5-tetrazol 1-yl, where: R is H or a pharmaceutically acceptable cation, or CO2R forms a pharmaceutically acceptable ester moiety; NR2R3, NR5R6 are the same or different and comprise a free or functionally modified amino group; OR4 comprises a free or functionally modified hydroxy group; Ha...
Arachidonic acid is then metabolized by enzymes such as LOX and COX, leading to the release of prostaglandins, thromboxanes, leukotrienes, and hydroxyeicosatetraenoic acids, which are mediators of inflammation [43]. Anti-inflammatories act either by inhibiting the enzymes (PLA2, COX, and LOX) ...
Lipoxygenases (LOXs) are nonheme, iron-containing enzymes that catalyse oxygenation of arachidonic acid (AA) to hydroperoxyeicosatetraenoic acids (HPETEs), which can be further converted to hydroxyeicosatetraenoic acids (HETEs), leukotrienes, lipoxins and hepoxilins [57,58]. In human, there are ...
丘脑-垂体-肾上腺轴HPETE:hydroperoxy-eicosatetraenoic acid 氢过氧二十碳四烯酸(合成白细胞三烯的中间产物)HPV:human papilloma virus 人类乳头瘤病毒HR:heart rate 心率HS:heparin sulfate 硫酸肝素HSE:herpes simplex encephalitis 单纯疱疹脑炎HSP:Henoch-Schnlein purpura 享舍二氏紫癜(即过敏性紫癜)5-HT:5-hydroxy...