REVERSE-USE DEPENDENCE OF ANTIARRHYTHMIC DRUGS: ROLE OF LATE SODIUM CURRENTHeart failureEchocardiographyDietDiastolic functionChronic expanding heamatomas may present as masses mimicking chest wall tumors. We report the case of a patient who was presented with a giant posterior extrathoracic chest wall ...
impaired function of the intestine and dependence on laxatives. Senna pods preparations should only be used if a therapeutic effect cannot be achieved by a change of diet or the administration of bulk forming agents. When senna pods preparations are administered to ...
activity.###Electrocardiographic Biomarkers for Detection of Drug-Induced Late Sodium Current Block.###Use of Antiarrhythmic Medications in Medicare Part D Patients With an Implantable Cardioverter-Defibrillator and Ventricular Tachycardia.###Myotonic dystrophy type 1.###Synthesis, antiarrhythmic activity...
The determinants of stereospecific binding of type I antiarrhythmic drugs to specific sites associated with the sodium channel were assessed using rat cardiac myocytes. The asymmetric carbon atoms of stereoisomers may be located at two s... RJ Hill,HJ Duff,RS Sheldon - 《Molecular Pharmacology》 ...
indicated for the treatment of addictions and dependence on psychoactive substances, such as: psychotropic medications, illicit drugs, tobacco and alcohol, which include, for example, but are not limited to, narcotics, benzodiazepines, marijuana, cocaine, methamphetamines, antidepressants, and ...
Antiarrhythmic effects of dehydroevodiamine in isolated human myocardium and cardiomyocytes. J Ethnopharmacol. 2014;153:753–62. Article CAS PubMed Google Scholar Liu AJ, Wang SH, Hou SY, Lin CJ, Chiu WT, Hsiao SH, Chen TH, Shih CM. Evodiamine induces transient receptor potential vanilloid-1...
Antiarrhythmic drugs have not previously... SJ Connolly,HJ Crijns,C Torp-Pedersen,... - 《Circulation》 被引量: 1300发表: 2009年 Development of a New Pharmacological Seizure Model: Effects of Anticonvulsants on Cortical‐and Amygdala‐Kindled Seizures in the Rat The potency of eight standard ...
Our results indicate that mutation-induced changes in the voltage-dependence of channel availability (inactivation) may act as determinants of flecainide block. The data further indicate that UDB by flecainide requires channel opening, but is not likely due to open channel block. Rather, flecainide ...
Changes of intracardiac conduction induced by antiarrhythmic drugs. Importance of use- and reverse use-dependence Child sexual abuse is an alarmingly common criminal offense. Whether prosecutions occur shortly after the alleged offense or after a lengthy delay, complai... HJGM Crijns - 《Psychology ...
It has become clear that a number of drugs having an unknown mechanism of action actually act by modulating sodium channel conductance, including local anaesthetics, class I antiarrhythmics and anticonvulsants. Neuronal sodium channel blockers have found application with their use in the treatment of...