Chronic kidney disease (CKD) is becoming an alarming health burden worldwide, however, there is still lack of early biomarkers and effective treatment options. Thus, in the upcoming era of precision medicine, searching for the sensitive, non-invasive biomarkers has been the cornerstone and major ...
Serum creatinine (SCr)- or urine output-based definitions of acute kidney injury (AKI) have important limitations in neonates. This study evaluates the diagnostic value of urinary biomarkers in very low-birth-weight (VLBW) infants receiving indomethacin for closure of a patent ductus arteriosus (PDA...
Publisher Correction: Novel Urinary Biomarkers For Improved Prediction Of Progressive eGFR Loss In Early Chronic Kidney Disease Stages And In High Risk Individuals Without Chronic Kidney DiseaseA correction to this article has been published and is linked from the HTML and PDF versions of this paper....
Rationale & Objective: Urinary biomarkers of injury, inflammation, and repair may help phenotype acute kidney injury (AKI) observed in clinical trials. We evaluated the differences in biomarkers between participants randomized to monotherapy or to combination renin-angiotensinaldosterone system (RAAS) block...
They are associated with early detection of kidney stress, allowing for targeted proactive intervention, and a significant decrease in postoperative stage 2/3 AKI without increases in cost or length of stay. Graphical abstract Response to urinary biomarkers drawn the morning after cardiac surgery. ...
The implementation of novel, reliable biomarkers for the early and differential diagnosis of acute kidney injury (AKI) could greatly improve the timely treatment and prevention of disease progression, particularly since the current gold standards for detecting kidney injury such as serum creatinine (SCr...
This study investigated for the first time whether podocyte related mRNA in urinary exosome could serve as novel biomarkers for kidney disease. Methods:Urine samples were collected from 32 patients of kidney disease who underwent kidney biopsy and 7 controls. CD2AP, NPHS2 and synaptopodin were ...
Askenazi. More information: "Acute Kidney Injury Urine Biomarkers in Very Low Birth Weight Infants," DOI: 10.2215/CJN.13381215 Journal information: Clinical Journal of the American Society of Nephrology Provided by American Society of Nephrology ...
BiomarkersEndocrinologyNephrologyThe aim of this study was to establish a peptidomic profile based on LC-MS/MS and random forest (RF) algorithm to distinguish the urinary peptidomic scenario of type 2 diabetes mellitus (T2DM) patients with different stages of diabetic kidney disease (DKD). Urine ...
before serum creatinine increases. Kidney injury molecule-1 (KIM-1) has not only been proposed as a diagnostic biomarker, but also as a pro-recovery marker for AKI [16,17,18,19]. Recently, the combination of two cell-cycle arrest biomarkers, insulin growth factor binding protein 7 (IGFBP7...