Science in medicine Uric acid transport and diseasedoi:10.1172/JCI42344.dietarySo, AlexanderThorens, BernardThe Journal of clinical investigationSo A, Thorens B. Science in medicine Uric acid transport and disease. 2010;120(6). doi:10.1172/JCI42344.dietary....
Uric acid transport and disease. J Clin Invest 120, 1791–9 (2010). 43. Tassone, F. et al. Vitamin D status in primary hyperparathyroidism: a Southern European perspective. Clin Endocrinol (Oxf) 79, 784–90 (2013). 44. Takahashi, S. et al. Decreased serum concentrations of 1,25(OH...
Uric acid transport and disease. J Clin Invest 120, 1791–9 (2010). 43. Tassone, F. et al. Vitamin D status in primary hyperparathyroidism: a Southern European perspective. Clin Endocrinol (Oxf) 79, 784–90 (2013). 44. Takahashi, S. et al. Decreased serum co...
Uric acid levels are associated with all-cause and cardiovascular disease mortality independent of systemic inflammation in men from the general population... Objective— The purpose of this study was to assess whether increasing serum uric acid (UA) levels are related to cardiovascular disease (CVD...
In this brief review and update, we try to cover recent developments in our understanding of uric acid transport by the kidney, the contribution of uric acid to renal stone disease, its potential role in progressive renal failure and, most recently, the novel and as yet unexplained link betwee...
Uric acid (UA; 7,9-hihydro-1H-purine-2,6,8(3H)-trione; empiric formula C5H4N4O3; molecular weight of 168.11 Da) is a heterocyclic organic compound and an end product of purine metabolism in humans and great apes. Historical records show that UA crystals were first described by Anton...
致。人尿酸经肾脏转运时需依赖肾小管上皮细胞上的转运蛋白,而人尿酸盐转运蛋白1(humanuricacidtransporter1, hURAT1)在尿酸盐重吸收过程中发挥重要作用。随着研究的不断深入,研究热点逐渐从hURAT1的结构和功能转为对基因 突变及药物对其影响等。该文对hURAT1及其影响因素进行综述。
Metabolic syndrome: an update on diagnostic criteria, pathogenesis, and genetic links 2018, Hormones Metabolic syndrome, diabetes, and hyperuricemia 2013, Current Opinion in Rheumatology Uric acid transport and disease 2010, Journal of Clinical Investigation Effects of febuxostat on metabolic and renal alt...
Uric acid: role in cardiovascular disease and effects of losartan. A substantial body of epidemiological and experimental evidence suggests that serum uric acid is an important, independent risk factor for cardiovascular a... Michael,Alderman,JV Kala,... - 《Current Medical Research & Opinion》 被...
Uric acid (UA) may be associated with the progression of Parkinson's disease and related neurodegenerative conditions; however, its association with Huntington's disease (HD) progression has not been explored. A secondary analysis of 347 subjects from the CARE-HD clinical trial was performed to ex...