emerging evidence underscores the pivotal role of physical stimuli in driving breast cancer metastasis. In this review, we summarize the changes in the mechanics of the breast cancer microenvironment
In contrast to the general belief, the crystallization of MIL-53 occurs via a solid-solid transformation mechanism, associated with the spontaneous release of monomeric aluminum. The role of DMF hydrolysis products, formate and dimethylamine, is established. Our study emphasizes the complexity of MOF...
causing a frameshift and the transactivation domain is replaced with seven specific amino acids [8]. Conversely, STAT3β plays a tumor suppressive role due to the lack of transactivation domain and commonly predicts a favorable outcome in tumor patients [9]. A recent review of the literature repo...
Conversely, STAT3β plays a tumor suppressive role due to the lack of transactivation domain and commonly predicts a favorable outcome in tumor patients [9]. A recent review of the literature reported that STAT3β cooper- ates with STAT3α and co-activators to form a ternary complex called "...
Moreover, a recent study showed that dihydroartemisinin (DHA) could promote pyroptosis in ESCC cells through the PKM2/caspase-8/caspase-3/GSDME axis, providing new insights into the role of DHA in ESCC [251]. Moreover, treatment with cisplatin was proven to cause the activation of CAPN1 and...
states, one cannot rely on these expressions anymore to make a statement whether or not NGA is forbidden, indicating the crucial role of such phase transitions for the observation of NGA. Finally, Krause et al. even showed that NGA cannot take place at global thermodynamic equilibrium, but ...
Regulation of cell cytoskeleton and membrane mechanics by electric field: role of linker proteins Biophys. J. (2009) D.R. Merrill et al. Electrical stimulation of excitable tissue: design of efficacious and safe protocols J. Neurosci. Methods (2005)View...
causing a frameshift and the transactivation domain is replaced with seven specific amino acids [8]. Conversely, STAT3β plays a tumor suppressive role due to the lack of transactivation domain and commonly predicts a favorable outcome in tumor patients [9]. A recent review of the literature repo...
As mentioned in the introduction, the VEGF receptor recognition (VEGF1–110) and the heparin binding (VEGF111–165) domains are connected by a linker sensitive to cleavage by plasmin. Plasmin plays a critical role in the VEGF signaling pathway by releasing the VEGF receptor recognition domain fro...
Introduction In the past decades, epigenetics has opened up new pathways of drug discovery [1]. Among epigenetic events, post-translational modifications (PTM) of histone proteins are of particular interest [2–4]. The epigenetic role of these PTMs can be explained by their altering effect on ...