Garten, W,Klenk, H.D.Understanding influenza virus pathogenicity. Trends in Microbiology . 1999Garten W, Klenk HD. Understanding influenza virus pathogenicity. Trends Microbiol. 1999;7(3):99-100.Garten W, Klenk
Recombinant NDV expressing soluble trimeric HA protein against highly pathogenic H5N1 influenza virus provides better efficacy than the membrane anchored HA suggesting that the type of antigenic foreign protein could be modulated for better protection (Cornelissen et al., 2010). 7. Newcastle disease ...
Influenza-induced thrombocytopenia is dependent on the subtype and sialoglycan receptor and increases with virus pathogenicity. Blood Adv. 4, 2967–2978 (2020). Article CAS PubMed PubMed Central Google Scholar Zhang, Y. et al. Mechanisms involved in the development of thrombocytopenia in ...
A. A new influenza virus virulence determinant: the NS1 protein four C-terminal residues modulate pathogenicity. Proc Natl Acad Sci U S A. 105, 4381–4386 (2008). 11. Smith, G. J. et al. Origins and evolutionary genomics of the 2009 swine-origin H1N1 influenza A epidemic. Nature 459,...
2022). Since 1900, zoonotic pathogens have been responsible for at least six worldwide viral pandemics, caused by HIV, SARS-CoV-2, and influenza viruses, as well as numerous human outbreaks of highly pathogenic avian influenza, Ebola virus, Hendra virus, Marburg virus, MERS-CoV, mpox (...
The phenomenon of antibody-dependent enhancement is not only seen in dengue virus infection, but it has also been found to be associated with several other viral infections such as influenza, enteroviruses, etc. [8,101,102]. In spite of numerous studies, the exact mechanism of ADE remains in...
Valentin-Weigand et al. (2020)posit that the influenza virus increases the pathogenic capacity ofS. suis so that, for specific strains, the disease can develop even in the absence of the key virulence factor suilysin. This highlights the importance of controlling coinfections for successfulS. sui...
Lactobacillus rhamnosus GG (LGG) is one of the most widely used probiotic strains. Various health effects are well documented including the prevention and treatment of gastro-intestinal infections and diarrhea, and stimulation of immune responses that pr
The PB1-F2 protein is relatively small when compared to other influenza proteins but is associated with a number of pathogenicity factors, including apoptosis, immunopathology, and secondary bacterial infection. Though a fair amount of work has been done to understand PB1-F2 in human and avian ...
(Treg) cell differentiation and depletion through the activation of TLR9168,169. Recent studies revealed that SARS CoV-2 mRNA vaccination exposes HIV to CD8+ T cells170. A small-molecule agonist of RIG-I, KIN1148, exhibits an adjuvant effect on influenza virus vaccine immunity171. The dsRNA ...