Fever (oral temperature of 100°F or higher) is a defense mechanism launched by the body to halt the progression of the virus or the bacteria; however, every person has a specific reaction to the pathogen. Some may develop all symptoms except fever, while others may feel feverish though the...
Secondary bacterial infection following influenza type A virus (IAV) infection is a major cause of morbidity and mortality during influenza epidemics. Streptococcus pneumoniae has been identified as a predominant pathogen in secondary pneumonia cases that develop following influenza. Although IAV has been ...
Comparison of High vs Standard Dose Influenza Vaccines in Pediatric Solid Organ Transplant Recipients Influenza virus is a significant pathogen in pediatric solid organ transplant (SOT) recipients. However, these individuals respond poorly to standard-dose (SD) inactivated influenza vaccine (IIV). Recent...
(e.g. humans, pigs, horses, seals). Currently,H3N2andH1N1are endemic among humans. At the time of writing, circulating H1N1 is thelineagethat caused a pandemic of mild influenza in 2009 (see below), called H1N1-pdm09.Influenza virus Bis almost exclusively ahuman pathogenalso causing...
Influenza A virus neuraminidase: regions of the protein potentially involved in virus-host interactions. PMID: 11040132 Transmission Bottleneck Size Estimation from Pathogen Deep-Sequencing Data, with an Application to Human Influenza A Virus. PMID: 28468874 ...
Influenza virus is a member of theOrthomyxoviridaefamily. There are three types of influenza virus based on its internal proteins ofnucleoproteinandmatrix protein, namely A, B, and C[1]. Among these,influenza A virusis the most prevalent pathogen for both humans and animals, causing the so-cal...
The primary H3N2 virus isolates were sequenced in-house and the sequences were provided by the Mount Sinai Pathogen Surveillance Program. These were then uploaded to GISAID and Genbank (see below). Reporting summary Further information on research design is available in the Nature Portfolio ...
Jamaican fruit bats (Artibeus jamaicensis) naturally harbor a wide range of viruses of human relevance. These infections are typically mild in bats, suggesting unique features of their immune system. To better understand the immune response to viral infe
for activation by an antigen before the body has ever encountered that antigen. Activators include intact microbes, Pathogen Associated Molecular Patterns (PAMPS), and host cellular constituents released during tissue injury. Of the effectors, the best studied are the antimicrobial peptides (AMPs) [...
Equine influenza virus has been recognized as a major respiratory pathogen in horses since about 1956. Disease symptoms caused by equine influenza virus can be severe, and are often followed by secondary bacterial infections. Two subtypes of equine influenza virus are recognized, namely subtype-1, ...