Contribution of Working Group I to the Sixth Assessment Report of the Intergovernmental Panel On Climate Change. [Masson-Delmotte, V., P. Zhai, A. Pirani, S.L. Connors, C. Péan, S. Berger, N. Caud, Y. Chen, L. Goldfarb, M.I. Gomis, M. Huang, K. Leitzell, E. Lonnoy, J....
Large-scale, long-term clinical studies will be necessary to determine whether FMTs can ameliorate obesity and other disorders associated with the metabolic syndrome. A comprehensive model for the influence of the microbiome on the host’s body weight has been developed (Sonnenburg and Bäckhed, ...
Estrogen is a master regulator of metabolic function (Rettberg et al., 2014), and the menopausal decline in E2 coincides with a bioenergetic deficit in the brain (Ding et al., 2013). Activated by E2, nuclear estrogen receptors, ER–α and ER-β, promote the expression of nuclear encoded ...
It is well established that alterations in phosphate metabolism have a profound effect on hard and soft tissues of the oral cavity. The present-day clinical form of osteonecrosis of the jaw (ONJ) was preceded by phosphorus necrosis of the jaw, ca. 1860.
In short, the CC mice are a large panel of multi-parent RI strains derived from eight founder strains representing the three major mouse subspecies (A/J, C57Bl/6J, 129Sv/ImJ, NOD/LtJ, NZO/H1J, CAST/EiJ, PWK/PhJ, and WSB/EiJ) that capture approximately 90% of the known genetic ...
Thus, the hypothalamic glia regulates different pathways that control systemic metabolism and sleep, and dysfunction in these processes may result in metabolic disorders (Fig. 1). 2.3. Synaptic plasticity Sleep has been described as pivotal in synaptic plasticity (Tononi and Cirelli, 2014). Synaptic...
Finally, Covid19 patients treated with steroids should avoid regular intake of foods that are high in salt and sugar in order to prevent the onset of metabolic disorders and arterial hypertension. 6. Conclusions SARS-CoV-2-positive or COVID-19 patients developing heart and brain dysfunction is ...
Am J Physiol Regul Integr Comp Physiol. 2015;309:R277–85. Article CAS PubMed PubMed Central Google Scholar Ostrowski S, Mesochina P, Williams JB. Physiological adjustments of sand gazelles (Gazella subgutturosa) to a boom-or-bust economy: standard fasting metabolic rate, total evaporative ...
Metabolic regulations are essential determinant of organismal lifespan, and this can be partly explained by modulation of cellular senescence. Overexpression of glycolytic enzymes, similar to hypoxic conditions, avoids senescence in murine embryonic fibroblasts (MEFs) cultivated at atmospheric oxygen, probably...
Even in cases where the clinical signs of disease are well described, little is known about how the presence of a pathogen may impact or interact with the microbial communities in the gut and subsequently influence the metabolic processes within the host. On the other hand, it is unclear ...