The MPC inhibitor UK5099 increases the glucose excursion seen during an intraperitoneal glucose tolerance test in C57BLK mice. UK 5099 上下游产品信息 上游原料 下游产品UK 5099 试剂级价格 更新日期产品编号产品名称CAS编号包装价格 2025/02/08 HY-15475 UK 5099UK-5099 56396-35-1 5mg 650元 2025/...
inhibits pyruvate-dependent oxygen consumption by rat heart mitochondria with an IC₅₀ value of 50 nM. UK-5099 has recently been shown to block pyruvate from entering the mitochondria, which forces the production of lactate in the hair follicle stem cells and accelerates hair growth in mice....
C57BLK mice are fasted for 16 h prior to glucose challenge. UK5099 (32 μmol/kg of body weight) or DMSO in PBS is injected into the intraperitoneal cavity 30 min before injecting glucose (1.5 mg of glucose/g of body weight). Blood glucose levels are measured at 0, 10, 20, 30, 60...
The MPC inhibitor UK5099 increases the glucose excursion seen during an intraperitoneal glucose tolerance test in C57BLK mice. 分子式 C18H11N2O2 分子量 288.30 CAS号 56396-35-1 运输条件 Room temperature in continental US; may vary elsewhere. 储存方式 Powder-20°C 3 years 4°C 2 years ...
in topical treatment in order to study its effect on hair cycle induction in experimental mice. Product description: UK-5099 (PF-1005023) is a potent inhibitor of the mitochondrial pyruvate carrier (MPC). UK-5099 (PF-1005023) inhibits pyruvate-dependent O2 consumption with an IC50 of 50 nM....
In vivo studyThe MPC inhibitor UK5099 increases the glucose excursion seen during an intraperitoneal glucose tolerance test in C57BLK mice. UK 5099 -Risk and Safety WGK Germany3 UK 5099 -Preparation solution concentration reference 1mg5mg10mg ...
动物实验C57BLK mice are fasted for 16 h prior to glucose challenge. UK5099 (32 μmol/kg of body weight) or DMSO in PBS is injected into the intraperitoneal cavity 30 min before injecting glucose (1.5 mg of glucose/g of body weight). Blood glucose levels are measured at 0, 10, 20,...
体内研究:UK-5099 slows the growth of patient-derived xenograft (PDX) tumors in mice without severe loss of animal body weight. 产品信息订购: 产品货号 产品名称 规格 价格 大包装及货期 abs810654 UK-5099 5mg 789.00 立即咨询 abs810654 UK-5099 10mg 1213.00 立即咨询 abs810654 UK-5099 50mg 4123....
After tumor volumes reached 50 mm3, the mice were intraperitoneally injected with either PBS, Syrosingopine (7.5 mg/kg) alone, UK-5099 (3 mg/kg) alone, or the combination of both drugs at the same doses. Tumor growth was closely monitored throughout the treatment period. At the ...
UK-5099HPLC–MS/MSMouse plasmaPharmacokineticsGlibenclamideA fast and sensitive HPLC–MS/MS method was developed, validated and successfully used for the determination of UK-5099 levels in mice after intraperitoneal administration. This study was the first report of the pharmacokinetic parameters of UK-...