This circRNA is highly conserva- tive across species, including humans (has_circ_0048966 in circBase, http://www.circbase.Org), mice, and bovines [56]. It shares about 77% similarity between chicken and mammals, and even 89% similarity among mammals (Fig. S3), ...
UV radiation also causes histological abnormalities, production of reactive oxygen species (ROS), and lipid peroxidation as shown in the integument of the earthworm species M. posthuma8. Despite the fact that both population and enzyme responses have been observed (see above), nothing is known ...
A circRNA (circINSR) formed by the exon 2 of linearINSR(552 bp) was identified from chicken pectoralis through ssRNA-Seq. This circRNA is highly conservative across species, including humans (has_circ_0048966 in circBase,http://www.circbase.Org), mice, and bovines [56]. It shares about...
Prior studies indicated that native (unfixed) chromosomes could be isolated from different cell types and species directly by staining with the DNA dyes Hoechst 33258 and chromomycin A3, and sorting chromosomes by flow cytometry36,37,38. This purification step has the additional advantage over ...
24and G9a/GLP25were shown to be important for the preservation of several DMRs in mouse ESCs. Nevertheless, their effect on imprinting in humans has not been thoroughly examined. Collectively, accumulating evidence suggests that imprinting might be regulated by multiple factors in a species-specific...
YAP (yes-associated protein) in renal proximal tubule cells apparently mitigated renal tubulointerstitial fibrosis in DKD mice [80]. Moxonidine is an inhibitor of central sympathetic outflow, which can act centrally to decrease sympathetic nervous activity [85]. Therefore, it is generally viewed as ...
Its involvement in cardiovascular disease has been well documented; for example, hepatocyte-specific deletion of ANGPTL4 attenuated obesity, liver steatosis, and atherosclerosis in high-fat-diet mice [32]. Atherosclerosis induced by chronic intermittent hypoxia in Apoe−/− mice was mitigated by ...
Functional investigation of candidate adaptive variation using novel techniques in molecular biology is slowly beginning to unravel how selection signals translate to changes in biology that underlie the phenotypic spectrum of our species. In addition to informing evolutionary hypotheses of adaptation, the ...
(2016) identified 410 lethal genes in mice. In general, the diagnosis of lethal genes is challenging for the following reasons: the difficulties of phenotype–genotype correlation, the many potential genes, and the variable phenotypes associated with the same genetic causes23. There is controversy ...
Preston et al., “Rapid and Sensitive Method for Evaluating Pseudomonas aeruginosa Virulence Factors during Corneal Infections in Mice,” Infection and Immunity 63:3497-3501 (1995). Pye et al., “Hemocytes Containing Polyphenoloxidase in Galleria Larvae after Injections of Bacteria,” Journal of Inv...