UGT2B7重组蛋白-UDP-glucuronosyltransferase 2B7 UGT2B7重组蛋白是一种来源于人类UGT2B7基因的重组蛋白,属于UGT(尿苷二磷酸葡萄糖转移酶)家族的一员。UGT2B7基因编码的蛋白质在人体内起到重要的代谢和排泄作用,参与药物代谢和脂肪酸代谢等生物学过程。UGT2B7重组蛋白作为一种生物工程技术产品,在药物研发和治疗领域...
Human UDP-Glucuronosyltransferase 2B7, UDP-Glucuronosyltransferases (UGTs), UGT2B isoform, UGT2B7, Polycyclic, Aromatic hydrocarbons (PAH), UGT2B7(H), UGT2B7(Y), Glu curon idation, GlucuronidationUDP-Glucuronosyltransferases (UGTs) are glycoproteins, localized in endoplasmic reticulum (ER) ...
UDP-glucuronosyltransferase 2B7 protein accumulates in cells when the cells enter stationary phase and growth inhibition. UGT2B7 protein is not expressed in exponentially growing ovarian tumor cells. Overexpression of UGT2B7 protein in human ovarian tumor cells results in cell growth arrest, ...
We have screened a cohort of 239 Norwegian cancer patients for sequence variation in the coding and regulatory regions of the UDP-glucuronosyltransferase 2B7 gene (UGT2B7) and analyzed the impact of gene variants on morphine glucuronidation in vivo. In all, 12 single nucleotide polymorphisms (SN...
Expression of UDP-glucuronosyltransferases (UGTs) 2B7 and 1A6 in the human brain and identification of 5-hydroxytryptamine as a substrate. Arch Biochem Biophys. 1999; 365: 156-62.King CD, Rios GR, Assouline JA, Tephly TR. 1999. Expression of UDP-glucuronosyltransferases (UGTs) 2B7 and...
Yuan, L., Qian, S., Xiao, Y., Sun, H. & Z., S. Homo- and hetero-dimerization of human UDP-glucuronosyltransferase 2B7 (UGT2B7) wild type and its allelic variants affect zidovudine glucuronidation activity. Biochem. Pharmacol. 95, 58-70 (2015)....
英文名称: UDP-GLUCURONOSYLTRANSFERASE 2B7 ISOZYME HUMAN 英文同义词: UGT2B7 HUMAN;UDP-GLUCURONOSYLTRANSFERASE 2B7 ISOZYME HUMAN;UDP-GLYCOSYLTRANSFERASE 2B7 ISOZYME HUMAN;UDP-glycosyltransferase 2B7, Isozyme human, UGT 2B7 Isozyme, Microsomes human;UGT 2B7 Isozyme, Microsomes human CAS号: 分子式:...
An association of UDP-glucuronosyltransferase 2B7 C802T (His268Tyr) polymorphism with bladder cancer in benzidine-exposed workers in China. EFFECT OF URIDINE DIPHOSPHATE-GLUCURONOSYLTRANSFERASE POLYMORPHISMS ON THE PLASMA CONCENTRATIONS OF MYCOPHENOLIC ACID IN TURKISH RENAL TRANSPLANT PATIENTS/TURK BOBREK...
Epirubicin glucuronidation is catalyzed by human UDP-glucuronosyltransferase 2B7. Epirubicin is one of the most active agents for breast cancer. The formation of epirubicin glucuronide by liver UDP-glucuronosyltransferase (UGT) is its ma... F Innocenti,L Iyer,J Ramirez,... - 《Drug Metabolism...
www.nature.com/scientificreports OPEN Inter-isoform Hetero- dimerization of Human UDP- Glucuronosyltransferases (UGTs) received: 21 June 2016 1A1, 1A9, and 2B7 and Impacts onaccepted:13September2016 Glucuronidation ActivityPublished:18November2016 Ling-Min Yuan*, Zhang-Zhao Gao*, Hong-Ying...