Grant DJ, Bell DA (2000) Bilirubin UDP-glucuronosyltransferase 1A1 gene polymorphisms: susceptibility to oxidative damage and cancer? Mol Carcinog 29: 198-204.DJ Grant,DA Bell.Bilirubin UDP-glucuronosyltransferase 1A1 gene polymorphisms: susceptibility to oxidative damage and cancer?.Molecular ...
三亚蟎对葡萄糖醛酸基转移酶(UDP-Glucuronosyltransferase)在雄及雌性大鼠均呈剂量关系,同时雄性大鼠分别增加39%及0.8 … ntur.lib.ntu.edu.tw|基于3个网页 2. 葡萄糖醛酸转移酶 ...许的胆红素葡糖醛酸(bilirubin glucuronides)。肝脏组织的分析中并无残余葡萄糖醛酸转移酶(UDP-glucuronosyltransferase)的…...
尿苷二磷酸葡萄糖醛酸转移酶(UDP-glucuronosyltransferases,UGTs)是人体Ⅱ相反应中最重要的酶之一,利用葡萄糖醛酸为糖基供体催化广泛的内源性和外源性化学物质进行结合反应,增加其极性而利于排出体外。 补充资料:尿苷二磷酸葡萄糖 尿苷二磷酸葡萄糖 uridine diphosphoglucose,UDPG ...
UDP-glucuronosyltransferase1A1 (UGT1A1) catalyses glucuronidation of bilirubin (the final break down product of heme which is produced mainly in the spleen and liver) and is located on the lumen of the endoplasmic reticulum (ER). To identify partner UGTs that form hetero-oligomers with UGT1A...
UDP-glucuronosyltransferase 1A1; UDPGT; UDPGT 1-1; UGT 1A; UGT-1A; UGT1; UGT1 01; UGT1*1; UGT1-01; UGT1.1; UGT1A; Ugt1a1; URIDINE DIPHOSPHATE GLUCURONOSYLTRANSFERASE, BILIRUBIN/PHENOL; URIDINE DIPHOSPHATE GLYCOSYLTRANSFERASE 1; URIDINE DIPHOSPHATE GLYCOSYLTRANSFERASE 1 FAMILY, POLYPEPTIDE A1...
UDP 葡糖醛酸基转移酶1家族多肽A1(UGT1A1)重组蛋白 Recombinant UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1) UGT1; GNT1; UGT1A; UDPGT; HUG-BR1; UGT1-1; Bilirubin-specific UDPGT isozyme 1
Relationship Between Bilirubin UDP-Glucuronosyl Transferase 1A1 Gene and Neonatal Hyperbilirubinemia CHING-SHAN HUANG, PI-FENG CHANG, MAY-JEN HUANG, EN-SUNG CHEN, KUN-LONG HUNG, AND KUO-INN TSOU Departments of Laboratory Medicine [C.S.H., M.J.H., E.S.C.] and Pediatrics [P.F.C., K...
Prolonged expression of bilirubin-UDP-glucuronosyl transferase-1 after adenovirus-mediated gene transfer into newborn Gunn rats . Marion Bessin Liver Research Center, Albert Einstein College of Medicine, Bronx, New YorkProlonged expression of bilirubin-UDP-glucuronosyl transferase-1 after adenovirus-medi...
Summary UDP-glucuronosyltransferases (UGTs) catalyse a major phase-II reaction of drug metabolism converting lipophilic xenobiotics (bilirubin, steroid hormones, retinoids etc.), drugs and dietary plant constituents into hydrophilic and excretable conjugates. UGTs are bound to the endoplasmic reticulum ...
A cDNA encoding a human bilirubin UDP-glucuronosyltransferase has been isolated and stably expressed in Chinese hamster V79 lung fibroblast cell line. Western blotting of cell homogenates with anti-UGT antibody revealed a highly expressed protein of approx. 55.5 kDa in size. The expressed enzyme ...