Medical Encyclopedia u·biq·ui·tin (yo͞o-bĭk′wĭ-tĭn) n. A small protein found in all eukaryotic cells that attaches to other proteins, thereby regulating their activity or location or marking them for degradation. [ubiquit(ous)+-in.] ...
In this chapter, we describe methods for the detection of ubiquitin ligase activity as well as the identification of substrates of a given ubiquitin ligase using two enrichment tools, TR-TUBE and anti-diGly antibody, coupled with mass spectrometry (MS). View chapterExplore book Related terms: ...
2006. Identification of the preferential ubiquitination site and ubiquitin-dependent degradation signal of Rpn4. J. Biol. Cell. 281 , 10657–10662.Ju, D. and Xie, Y. (2006) Identification of the preferential ubiquitination site and ubiquitin-dependent degradation signal of Rpn4. J. Biol. Chem...
Exploration of the mechanisms by which cytokines of the TNF family induce cell death has led to the identification of a form of programmed cell death called “necroptosis” in which the protein mixed lineage kinase domain-like molecule (MLKL), upon its phosphorylation by the protein kinase RIPK...
studies with conditional knockouts of A20 in mice further underline the importance of A20 during infections and in maintenance of homeostasis (summarized by Martens and van Loo [66]). Inactivation of A20 by mutagenesis of the DUB active site (C103A) or disruption of ZnF4 function (C609A, C...
Identification of the Preferential Ubiquitination Site and Ubiquitin-dependent Degradation Signal of Rpn4 - ScienceDirect Donghong Ju,Youming Xie - 《Journal of Biological Chemistry》 被引量: 0发表: 2006年 Rsp5 Ubiquitin-Protein Ligase Mediates DNA Damage-Induced Degradation of the Large Subunit of ...
A total of 121,742 ubiquitination sites were collected from PLMD database (http://plmd.biocuckoo.org/) and the proteins were retrieved from UniProt (https://www.uniprot.org/). The data is provided on websitehttps://github.com/Sunmile/DeepUbiand the file name is “Raw Data”. ...
If you agree, we’ll use precise geolocation data and identification through device scanning. You may click to consent to our processing as described above. Click ‘Customize cookies’ to decline these cookies, make more detailed choices, or learn more. You can change your choices at any time...
identification of htlv-i tax trans-activator mutants exhibiting novel transcriptional phenotypes. genes dev. 1990, 4: 1875-1885. 10.1101/gad.4.11.1875. article cas pubmed google scholar kudo n, wolff b, sekimoto t, schreiner ep, yoneda y, yanagida m, horinouchi s, yoshida m: leptomycin b ...
Identification and Characterization of Mutations in Ubiquitin Required for Non-covalent Dimer Formation M Gabrielsen,L Buetow,D Kowalczyk,... - 《Elsevier Sponsored Documents》 被引量: 0发表: 2019年 Novel calcium-dependent mechanisms of NF-B activation 1 T Cell Receptor-Induced NF-B Signaling and...