et al. Differential organ phenotypes after postnatal Igf1r gene conditional deletion induced by tamoxifen in UBC- CreERT2; Igf1r fl/fl double transgenic mice. Transgenic Res 24, 279-294 (2015).Icíar PaulaLópez, LourdesRodriguez-de la Rosa, Rosete SofiaPais, SergioPiñeiro-Hermida, Raquel...
Ubc9fl//ROSA26-CreERT2 mice died within 6 days of 4-hydroxytamoxifen injection, losing 20% or less of their body weight and developing severe diarrhea on the second day after injection. Surprisingly, other epithelial tissues appeared to be unaffected at that stage. Decreased sumoylation led ...